不同年龄段胚胎停育患者中医症状与证素的分布特点  

Distribution characteristics of traditional Chinese medicine symptoms and syndrome elements in different age groups of patients with embryo damage

作　　者：兰萌 林雪娟[1,2,3] 陈杭 黄琰钰 吴冬梅 刘文杰[5] 刘艳红 LAN Meng;LIN Xue-juan;CHEN Hang;HUANG Yan-yu;WU Dong-mei;LIU Wen-jie;LIU Yan-hong(Research Base of Traditional Chinese Medicine Syndrome,Fujian University of Traditional Chinese Medicine,Fuzhou 350122,China;Key Laboratory of Chinese Medicine Health Status Differentiation of Fujian Province,Fuzhou 350122,China;Collborative Innovation of Health Management of Traditional Chinese Medicine of Fujian Province in 201l,Fuzhou 350122,China;The Second People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine,Fuzhou 350003,China;Jinjiang Hospital of Traditional Chinese Medicine Affllated toFujian University of Traditional ChineseMedicine,Jinjiang 362200,China)

机构地区：[1]福建中医药大学中医证研究基地,福州350122 [2]福建省中医健康状态辨识重点实验室,福州350122 [3]福建省2011中医健康管理协同创新中心,福州350122 [4]福建中医药大学附属第二人民医院,福州350003 [5]福建中医药大学附属晋江中医院,晋江362200

出　　处：《中华中医药杂志》2023年第1期423-427,共5页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金项目(No.81230087);福建省自然科学基金项目(No.2021J01931)。

摘　　要：目的:探讨不同年龄段胚胎停育患者中医症状与证素的分布特点。方法:以210例胚胎停育患者为研究对象,采用证素辨证方法获取证素及相应积分,分析低、中、高龄3个年龄段胚胎停育患者中医证素分布特点。结果:胚胎停育患者常见的临床表现为乳房胀(经前)、月经夹块、四肢凉、月经量少等;胚胎停育≥2次患者的年龄显著大于胚胎停育1次患者的年龄(P<0.05),且在中龄组和高龄组中的占比升高。低、中、高龄3组患者的病位证素均以肝、胞宫、肾为主,病性证素均以气滞、气虚、阳虚为主。结论:高龄是胚胎停育的重要因素,随年龄的增大胚胎停育风险增高;不同年龄段胚胎停育患者的主要病位均在肝、胞宫、肾,病性均以气滞、气虚、阳虚为主,表现为虚实夹杂的病理状态,肝郁气滞是胚胎停育患者的重要病理特点。Objective:To investigate the distribution characteristics of traditional Chinese medicine(TCM)symptoms and syndrome elements in patients with embryo damage in different ages groups.Methods:A total of 210 patients with embryo damage were selected as the research objects.Forensics and corresponding integrals were obtained by syndrome differentiation method to analyze the distribution characteristics of TCM syndrome elements in patients with embryo damage in three ages:low,middle and old.Results:The common clinical manifestations of the patients were breast distension(premenstrual),menstrual cramps,cold limbs,less menstrual volume,etc..The age of the patients with≥2 embryo damage was significantly higher than that of the patients with 1 embryo damage(P<0.05),and the proportion of the patients in the middle age group and the elderly group was increased.In the three groups of patients with low,middle and old age,the disease location syndrome elements were mainly liver,cell palace and kidney,and the disease syndrome elements were mainly qi stagnation,qi deficiency and yang deficiency.Conclusion:Old age is an important factor of embryo damage,and the risk of embryo damage increases with the increase of age.The main disease sites of patients with embryo damage in different age groups were liver,cellular palace and kidney,and the diseases were mainly qi stagnation,qi deficiency and yang deficiency.Liver qi stagnation was an important pathological characteristic of patients with embryo damage.

关 键 词：不同年龄段 胚胎停育 中医症状 证素 病位证素 病性证素 

分 类 号：R271.4[医药卫生—中医妇科学]