急性缺血性脑卒中病人医院感染与卒中复发风险研究  

Risk of nosocomial infection and stroke recurrence in patients with acute ischemic stroke

作　　者：胡富勇 芈静 潘宇芹 郭华陵 杨静[2] 吴君仓[3] 刘秋皖 吴竹青 群森 HU Fu-yong;MI Jing;PAN Yu-qin;GUO Hua-ling;YANG Jing;WU Jun-cang;LIU Qiu-wan;WU Zhu-qing;QUN Sen(School of Public Health,Bengbu Medical College,Bengbu Anhui 233030;Department of Neurology,The First Affiliated Hospital of University of Science and Technology of China,Hefei Anhui 230001;Department of Neurology,The NO.2 People′s Hospital of Hefei,Hefei Anhui 230032,China)

机构地区：[1]蚌埠医学院公共卫生学院,安徽蚌埠233030 [2]中国科学技术大学第一附属医院神经内科,安徽合肥230001 [3]安徽省合肥市第二人民医院神经内科,安徽合肥230032

出　　处：《蚌埠医学院学报》2023年第1期122-126,共5页Journal of Bengbu Medical College

基　　金：安徽省重点研究与开发计划项目(202004j07020014);安徽省合肥市自主创新政策“借转补”项目(J2019Y01);安徽省高等学校自然科学研究项目(KJ2018A0991);蚌埠医学院自然科学研究重点项目(2020byzd042)。

摘　　要：目的:研究急性缺血性脑卒中(acute ischemic stroke,AIS)病人医院感染与脑卒中复发之间的关系。方法:采用队列研究,收集121例AIS病人基本资料,随访收集病人卒中复发情况。Cox回归分析医院感染是否为脑卒中复发的独立危险因素。结果:121例AIS病人中医院感染的发生率为19.8%(95%CI:0.127~0.269),卒中复发率为26.4%(95%CI:0.185~0.343),医院感染导致卒中复发的HR为6.485(95%CI:2.984~14.091)。结论:AIS病人医院感染可能是卒中复发的一个独立风险因素。Objective:To investigate the relationship between nosocomial infection and stroke recurrence in patients with acute ischemic stroke(AIS).Methods:A cohort study was used to collect medical data on 121 AIS patients,and the recurrence of stroke was collected by follow-up.Cox regression was used to analyze the association between nosocomial infection and stroke recurrence.Results:In 121 patients,the prevalence of nosocomial infection was 19.8%(95%CI:0.127-0.269),the incidence of stroke recovery was 26.4%(95%CI:0.185-0.343),and the HR of stroke recurrence caused by nosocomial infection was 6.485(95%CI:2.984-14.091).Conclusions:Nosocomial infection in AIS patients may be an independent risk factor for stroke recurrence.

关 键 词：医院感染 缺血性脑卒中 卒中复发 

分 类 号：R181[医药卫生—流行病学] R743.3[医药卫生—公共卫生与预防医学]