Fine particulate matter and cardiorespiratory health in China:A systematic review and meta-analysis of epidemiological studies  

作　　者：Huihuan Luo Qingli Zhang Yue Niu Haidong Kan Renjie Chen 

机构地区：[1]School of Public Health,Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment,Fudan University,Shanghai 200032,China

出　　处：《Journal of Environmental Sciences》2023年第1期306-316,共11页环境科学学报（英文版）

基　　金：funded by the National Key Research and Development Program of China(No.2019YFC0214801);National Natural Science Foundation of China(Nos.92043301 and 92143301)。

摘　　要：This review aimed to systematically summarize the epidemiological literature on the cardiorespiratory effects of PM_(2.5)published during the 13^(th) Five-Year Plan period(2016-2020)in China.Original articles published between January 1,2016 and June 30,2021 were searched in PubMed,Web of Science,the China National Knowledge Internet Database and Wanfang Database.Random-or fixed-effects models were used to pool effect estimates where appropriate.Of 8558 records identified,145 met the full eligibility criteria.A 10μg/m^(3) increase in short-term PM_(2.5)exposure was significantly associated with increases of 0.70%,0.86%,0.38%and 0.96%in cardiovascular mortality,respiratory mortality,cardiovascular morbidity,and respiratory morbidity,respectively.The specific diseases with significant associations included stroke,ischemic heart disease,heart failure,arrhythmia,chronic obstructive pulmonary disease,pneumonia and allergic rhinitis.The pooled estimates per 10μg/m^(3) increase in long-term PM_(2.5)exposure were 15.1%,11.9%and 21.0%increases in cardiovascular,stroke and lung cancer mortality,and 17.4%,11.0%and 4.88%increases in cardiovascular,hypertension and lung cancer incidence respectively.Adverse changes in blood pressure,heart rate variability,systemic infiammation,blood lipids,lung function and airway infiammation were observed for either short-term or long-term PM_(2.5)exposure,or both.Collectively,we summarized representative exposure-response relationships between short-and long-term PM_(2.5)exposure and a wide range of cardiorespiratory outcomes applicable to China.The magnitudes of estimates were generally smaller in short-term associations and comparable in long-term associations compared with those in developed countries.Ourfindings are helpful for future standard revisions and policy formulation.There are still some notable gaps that merit further investigation in China.

关 键 词：Fine particulate matter Air pollution Cardiovascular system Respiratory system Mortality Morbidity Epidemiological studies 

分 类 号：X513[环境科学与工程—环境工程] R181.3[医药卫生—流行病学]