运脾化浊颗粒治疗代谢综合征疗效观察  

Observation on Therapeutic Effect of Yunpi Huazhuo Granules in Treating Metabolic Syndrome

作　　者：王振强[1] 马远新[1] 张庆江 吕树泉[1] 冯玲[2] 张淑芳[1] 苏秀海[1] 王庆海[1] WANG Zhen-qiang;MA Yuan-xin;ZHANG Qing-jiang;LV Shu-quan;FENG Ling;ZHANG Shu-fang;SU Xiu-hai;WANG Qing-hai(Department of Traditional Chinese Medicine,Cangzhou Hospital of Integrated Traditional Chineseand Western medicine,Cangzhou 061001,China;Department of Traditional Chinese Medicine,Guang'anmen Hospital,Chinese Academy of Chinese Medicine Sciences,Beijing 100051,China)

机构地区：[1]河北省沧州中西医结合医院中医内科,沧州061001 [2]中国中医科学院广安门医院中医内科,北京100051

出　　处：《微循环学杂志》2023年第1期43-47,共5页Chinese Journal of Microcirculation

基　　金：河北省中医药管理局资助课题(2016143)。

摘　　要：目的:观察运脾化浊颗粒治疗代谢综合征(MS)的疗效。方法:选取2018-01-2020-12本院收治的200例MS患者,按随机数字表法将其分为2组,对照组(n=100)给予常规综合治疗,研究组(n=100)在对照组治疗基础上给予运脾化浊颗粒。比较两组内脏脂肪体积、代谢指标水平变化及疗效差异。结果:研究组总有效率高于对照组(P<0.05)。治疗前,两组内脏脂肪体积及各相关代谢指标水平比较,差异无统计学意义(P>0.05)。治疗后两组患者内脏脂肪体积均降低(P<0.05),且研究组较对照组降低更明显(P<0.05)。治疗中,研究组各项代谢指标优于治疗前(P<0.05);治疗后,两组各项代谢指标优于治疗前(P<0.05);治疗中、治疗后,研究组各项代谢指标优于对照组(P<0.05)。结论:运脾化浊颗粒治疗MS疗效肯定,能缩小内脏脂肪体积,改善机体代谢。Objective: To observe the curative effect of Yunpi Huazhuo Granule on the treatment of metabolic syndrome(MS). Method: Two-hundred MS patients from January 2018 to December 2020 were selected and divided into 2 groups according to the random number table method. The control group(n=100) was given routine comprehensive treatment, the study group(n=100) was given Yunpi Huazhuo Granules on the basis of the control group. The changes of visceral fat volume, metabolic index level and curative effect between the two groups were compared. Results: The total effective rate of the study group was higher than that of the control group(P<0.05). Before treatment, there was no statistically significant difference between the two groups in visceral fat volume and the levels of related metabolic indicators(P>0.05). After treatment, the visceral fat volume of patients in both groups was decreased(P<0.05), and the reduction in the study group was more significant than that in the control group(P<0.05). During treatment, the metabolic indexes of the study group were better than those before treatment(P<0.05);after treatment, the metabolic indexes of the two groups were better than those before treatment(P<0.05);during and after treatment, the metabolic indexes of the study group were better than the control group(P<0.05). Conclusion: Yunpi Huazhuo Granule is effective in treating MS, which can reduce the volume of visceral fat and improve the body’s metabolism.

关 键 词：运脾化浊颗粒 代谢综合征 疗效 内脏脂肪体积 

分 类 号：R589[医药卫生—内分泌]