埃德蒙顿症状评估量表在针灸治疗癌痛患者中的应用:基于肿瘤科住院患者的回顾性分析和一项前瞻性预试验  

Application of Edmonton symptom assessment system in daily cancer pain management by acupuncture:retrospective analysis of data from an inpatient oncology department and a pilot prospective study

作　　者：陈耿杭 范美玉 常雪松 吴泽霞 张海波 郭新峰 何怡瀚 Geng-hang CHEN;Mei-yu FAN;Xue-song CHANG;Ze-xia WU;Hai-bo ZHANG;Xin-feng GUO;Yi-han HE(Guangdong Provincial Hospital of Chinese Medicine,The Second Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangdong Provincial Academy of Chinese Medical Sciences,Guangzhou 510120,China;State Key Laboratory of Dampness Syndrome of Chinese Medicine,The Second Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510120,China)

机构地区：[1]广东省中医院,广州中医药大学第二附属医院,广东省中医科学院,中国广州510120 [2]广州中医药大学第二附属医院省部共建中医湿证国家重点实验室,中国广州510120

出　　处：《World Journal of Acupuncture-Moxibustion》2023年第1期51-57,共7页世界针灸杂志（英文版）

基　　金：Supported by the National Natural Science Foundation of China(no.82004447);Guangdong Basic and Applied Basic Research Foundation(no.2021A1515011597);Discipline-Collaborative Innovation Team for"Double First-Class"and High-Level University in Guangzhou University of Chinese Medicine(no.2021XK08)。

摘　　要：Background:As pain is the most prominent clinical symptom for cancer patients and closely related to other symptoms,it is necessary to have a comprehensive assessment on promising intervention to improve pain management.Methods:A retrospective study of 489 inpatient cancer patients(1081 visits)was conducted by querying the electronic medical record database to test the reliability and validity of the Edmonton Symptom Assessment System.Data from a pilot prospective randomized controlled study on acupuncture for cancer pain was analyzed to validate the Edmonton Symptom Assessment System(ESAS)as the primary outcome in the integrative oncology research.Results:In the retrospective analysis,scores of the numerical rating scale(NRS)and the ESAS total score were significantly correlated(r=0.15,P=0.02),and the correlation coefficient between NRS and pain sub-scale in ESAS was 0.47(P<0.001).The pilot study showed the proportions of participants experiencing more than a 2-point reduction in NRS at the end of the treatment were 80%(n=12/15)in the acupuncture group and 50%(n=7/14)in the control group,without a significant difference between groups(P=0.13).For the total scores of ESAS,more responders were found in the acupuncture group(n=13/15)compared to that in the control group(n=7/14),with no significant difference between groups(P=0.05).Conclusions:ESAS is suitable for the comprehensive assessment in patients with cancer pain and could be an appropriate outcome measurement in acupuncture research for cancer pain.Trial registration:Registered on 09/07/2018 with ChiCTR1800017023(https://www.chictr/org.cn/edit.aspx?pid=28879&htm=4)

关 键 词：Cancer pain Edmonton Symptom Assessment System(ESAS) ACUPUNCTURE Integrative oncology Numerical rating scale(NRS) 

分 类 号：R246.5[医药卫生—针灸推拿学]