肝素结合蛋白及血清淀粉样蛋白A在AECOPD合并肺部感染中的研究进展  

Advances in the study of heparin-binding protein and serum amyloid A in AECOPD co-infection of the lung

作　　者：马葳 李梅华[1] 蒋菁 刘兴许 杨丽芬[1] 李丽[1] MA Wei;LI Meihua;JIANG Jing;LIU Xingxu;YANG Lifen;LI Li(Deft.of Respiratory and Critical Care Medicine,The First People’s Hospital of Kunming,Kunming Yunnan 650011,China)

机构地区：[1]昆明市第一人民医院呼吸与危重症医学科,云南昆明650011

出　　处：《昆明医科大学学报》2023年第2期172-176,共5页Journal of Kunming Medical University

基　　金：国家自然科学基金资助项目(82060127)。

摘　　要：慢性阻塞性肺疾病是一种常见、多发、死亡率较高的呼吸系统慢性疾病,感染是造成慢阻肺急性加重最主要的诱因;近年来,血清淀粉样蛋白A及肝素结合蛋白作为较新的感染指标,因其反应迅速,检验灵敏度、特异度较高等优势,在呼吸系统疾病领域越来越受到关注。将对HBP、SAA在慢阻肺急性加重合并肺部感染方面的研究进展进行概括归纳,为临床诊断和评估预后提供参考。Chronic obstructive pulmonary disease is a common,frequent and high mortality chronic disease of the respiratory system,while infection is the main cause of acute exacerbation of COPD;In recent years,serum amyloid A and heparin-binding protein have received increasing attention in the field of respiratory diseases as newer indicators of infection because of their rapid response,sensitivity and specificity;This article will summarize the research progress of HBP and SAA in acute exacerbation of chronic obstructive pulmonary disease combined with pulmonary infections,and provide a reference for clinical diagnosis and assessment of prognosis.

关 键 词：慢性阻塞性肺疾病 慢性阻塞性肺疾病急性加重 肝素结合蛋白 血清淀粉样蛋白A 

分 类 号：R563.9[医药卫生—呼吸系统]