针刺治疗脑梗死恢复期临床研究  

Clinical Study on Acupuncture for Cerebral Infarction in Convalescence

作　　者：王志峰[1] WANG Zhifeng

机构地区：[1]济源市中医院针灸推拿科,河南济源459000

出　　处：《新中医》2023年第1期155-158,共4页New Chinese Medicine

摘　　要：目的:观察针刺对脑梗死恢复期患者神经功能及血清细胞间黏附分子-1 (ICAM-1)、胰岛素样生长因子-1 (IGF-1)水平的影响。方法:将94例脑梗死恢复期患者以随机数字表法分为对照组与治疗组各47例,2组均实施基础治疗,对照组给予常规西药治疗,治疗组在对照组基础上给予针刺治疗。观察2组治疗后临床疗效、不良反应及治疗前后美国国立卫生研究院卒中量表(NIHSS)评分、自理能力评估量表(Barthel)评分、血清ICAM-1、 IGF-1水平。结果:治疗组临床总有效率93.62%,高于对照组70.21%(P<0.05)。治疗前,2组NIHSS、Barthel评分比较,差异无统计学意义(P>0.05);治疗后,2组NIHSS评分降低(P<0.05),Barthel评分升高(P<0.05),且治疗组NIHSS评分低于对照组,Barthel评分高于对照组(P<0.05)。治疗前,2组血清ICAM-1、IGF-1水平比较,差异无统计学意义(P>0.05);治疗后,2组血清ICAM-1水平降低(P<0.05),IGF-1水平升高(P<0.05),且治疗组血清ICAM-1水平低于对照组,IGF-1水平高于对照组(P<0.05)。2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:针对脑梗死恢复期采用针刺治疗临床疗效显著,有利于改善患者神经功能,提高生活自理能力,可能与针刺能有效调节血清ICAM-1、IGF-1水平有关。Objective: To observe the effect of acupuncture on neurological function and levels of intercellular adhesion molecule-1(ICAM-1) and insulin-like growth factor-1(IGF-1) in serum in patients with cerebral infarction in convalescence. Methods:A total of 94 cases of patients with cerebral infarction in convalescence were divided into the control group and the treatment group according to the random number table method,with 47 cases in each group. Both groups were given basic treatment;the control group was treated with routine western medicine,and the treatment group was additionally treated with acupuncture based on the treatment of the control group. The scores of National Institutes of Health Stroke Scale(NIHSS) and Barthel Index for activities of daily living(Barthel), the levels of ICAM-1 and IGF-1 in serum before and after treatment,and the clinical effects and the adverse reactions after treatment in the two groups were observed. Results:The total clinical effective rate was 93.62% in the treatment group,higher than that of 70.21% in the control group(P<0.05). Before treatment, there was no significant difference being found in the comparison of scores of NIHSS and Barthel between the two groups(P>0.05).After treatment,the NIHSS scores in the two groups were decreased(P<0.05),and Barthel scores were increased(P<0.05);the NIHSS score in the treatment group was lower,and Barthel score was higher than that in the control group(P<0.05). Before treatment,there was no significant difference being found in the comparison of levels of ICAM-1 and IGF-1 in serum between the two groups(P>0.05). After treatment,the ICAM-1 levels in serum in the two groups were decreased(P<0.05),and IGF-1 levels in serum were increased(P<0.05);the ICAM-1 level in serum in the treatment group was lower,and the IGF-1 level in serum was higher than that in the control group(P<0.05). There was no significant difference being found in the comparison of incidence of adverse reactions between the two groups(P>0.05). Conclusion: The application o

关 键 词：脑梗死 恢复期 针刺 神经功能 血清细胞间黏附分子-1 胰岛素样生长因子-1 

分 类 号：R246.6[医药卫生—针灸推拿学] R743.33[医药卫生—中医临床基础]