解郁百合方联合五行音乐疗法治疗围绝经期综合征情绪障碍临床研究  

Clinical Study on Jieyu Baihe Formula Combined with Five-Phase Music Therapy for Emotional Disorder in Perimenopausal Syndrome

作　　者：王素素 戴慧梅 蔡洁茹 蒋姣艳 WANG Susu;DAI Huimei;CAI Jieru;JIANG Jiaoyan

机构地区：[1]温州市人民医院,浙江温州325000

出　　处：《新中医》2023年第1期187-191,共5页New Chinese Medicine

基　　金：温州市科学技术局项目(Y20180388)。

摘　　要：目的:观察解郁百合方联合五行音乐疗法治疗围绝经期综合征(PPS)情绪障碍的临床疗效。方法:选取98例PPS情绪障碍患者,按随机数字表法分为观察组及对照组各49例。对照组予以芬吗通口服,观察组在对照组基础上予以解郁百合方联合五行音乐疗法治疗。比较2组临床疗效,比较2组治疗前后汉密顿焦虑量表(HAMA)、17项版汉密尔顿抑郁量表(HAMD-17)、改良Kupperman指数、匹茨堡睡眠质量指数(PSQI)、性激素[血清雌二醇(E_(2))、促卵泡激素(FSH)]水平的变化。结果:经秩和检验,观察组临床疗效优于对照组(P<0.05)。治疗后,2组HAMA、HAMD-17、改良Kupperman指数评分、PSQI评分均较治疗前下降(P<0.05),观察组上述4项评分低于对照组(P<0.05)。治疗后,2组E_(2)水平均较治疗前上升,FSH水平均较治疗前下降,差异均有统计学意义(P<0.05);观察组E_(2)水平高于对照组,FSH水平低于对照组,差异均有统计学意义(P<0.05)。治疗期间2组均未出现严重药物不良反应。结论:解郁百合方联合五行音乐疗法治疗PPS情绪障碍的临床疗效良好,有助于缓解患者焦虑、抑郁等症状,改善性激素水平,提高睡眠质量。Objective:To observe the clinical effect of Jieyu Baihe Formula combined with five-phase music therapy for emotional disorder in perimenopausal syndrome(PPS). Methods:A total of 98 cases of PPS patients with emotional disorder were divided into the observation group and the control group according to the random number table method,with 49 cases in each group. The control group was given oral administration of Femoston, and the observation group was additionally treated with Jieyu Baihe Formula combined with five-phase music therapy based on the treatment of the control group. The clinical effects in the two groups were compared. Before and after treatment,the changes in Hamilton Anxiety Scale(HAMA), Hamilton Depression Scale(HAMD-17), Modified Kupperman Scale, Pittsburgh Sleep Quality Index(PSQI), and levels of sex hormones including estrogen(E_(2)) and follicle stimulating hormone(FSH) in serum were compared between the two groups. Results: The clinical effect in the observation group was better than that in the control group(P<0.05). After treatment,the scores of HAMA,HAMD-17,Modified Kupperman Scale and PSQI in the two groups were decreased when compared with those before treatment(P<0.05), and the above four scores in the observation group were lower than those in the control group(P<0.05). After treatment,the E_(2) levels in the two groups were increased when compared with those before treatment(P<0.05),and the FSH levels were decreased,differences being significant(P<0.05);the E_(2) level in the observation group was higher, and FSH level was lower than that in the control group, differences being significant(P<0.05). During treatment, there was no serious adverse reaction of drug in the two groups. Conclusion: Jieyu Baihe Formula combined with five-phase music therapy has a good clinical effect in treating emotional disorder in PPS,and is helpful to relieve symptoms including anxiety and depression,and improve levels of sex hormones and quality of life.

关 键 词：围绝经期综合征 情绪障碍 解郁百合方 五行音乐疗法 

分 类 号：R271.116[医药卫生—中医妇科学]