高通量血液透析对尿毒症患者心肌损伤标志物及心功能指标的影响  

Impact of High-Flux Hemodialysis on Myocardial Injury Markers and Cardiac Function Indicators of Uremic Patients

作　　者：宋莎莎 张宝冲 李茹曼 王伟[1] SONG Shasha;ZHANG Baochong;LI Ruman;WANG Wei(Hemodialysis Room,He'nan University Huaihe Hospital,Kaifeng 475000,China)

机构地区：[1]河南大学淮河医院血液透析室,河南开封475000

出　　处：《临床医学工程》2023年第2期163-164,共2页Clinical Medicine & Engineering

摘　　要：目的探讨高通量血液透析(HFHD)治疗尿毒症对患者心肌损伤标志物及心功能的影响。方法80例尿毒症患者随机分为两组各40例,对照组采用常规血液透析治疗,实验组采用HFHD治疗,比较两组的心肌损伤标志物(BNP、cTnT)以及心功能(LVEF、LVEDD、LVESD、LVPWT)。结果治疗后,两组的BNP、cTnT、LVEDD、LVESD、LVPWT水平均较治疗前降低,LVEF水平均升高(P<0.05);实验组的BNP、cTnT、LVEDD、LVESD、LVPWT水平均低于对照组,LVEF水平高于对照组(P<0.05)。结论HFHD治疗尿毒症可明显降低患者的心肌损伤标志物水平,改善患者心功能。Objective To explore the impact of high-flux hemodialysis(HFHD)on myocardial injury markers and cardiac function of uremic patients.Methods 80 patients with uremia were randomly divided into two groups,with 40 cases in each group.The control group was treated with conventional hemodialysis,and the experimental group was treated with HFHD.The myocardial injury markers(BNP,cTnT)and cardiac function(LVEF,LVEDD,LVESD,LVPWT)were compared between the two groups.Results After treatment,the levels of BNP,cTnT,LVEDD,LVESD and LVPWT in the two groups were lower than those before treatment,and the levels of LVEF were higher than those before treatment(P<0.05);The levels of BNP,cTnT,LVEDD,LVESD and LVPWT in the experimental group were lower than those in the control group,and the level of LVEF was higher than that in the control group(P<0.05).Conclusions HFHD in the treatment of uremia can significantly reduce the levels of myocardial injury markers and improve cardiac function of patients.

关 键 词：高通量血液透析 尿毒症 心肌损伤标志物 心功能 

分 类 号：R459.5[医药卫生—治疗学]