替格瑞洛联合阿司匹林对急性心肌梗死患者左心室功能指标及炎性因子水平的影响  

Impact of Ticagrelor Combined with Aspirin on Left Ventricular Function Indicators and Levels of Inflammatory Factors in Patients with Acute Myocardial Infarction

作　　者：邓林 季翔 魏艳霞[1] DENG Lin;JI Xiang;WEI Yanxia(Department of Rehabilitation Medicine,Nanyang Central Hospital,Nanyang 473000,China)

机构地区：[1]南阳市中心医院康复医学科,河南南阳473000

出　　处：《临床医学工程》2023年第2期199-200,共2页Clinical Medicine & Engineering

摘　　要：目的探讨替格瑞洛联合阿司匹林在急性心肌梗死(AMI)患者中的应用效果。方法120例AMI患者随机分为两组,对照组给予氯吡格雷联合阿司匹林治疗,观察组给予替格瑞洛联合阿司匹林治疗,比较两组的左心室功能指标、炎性因子水平及不良反应。结果治疗后,观察组的LVEDD、IL-6、TNF-α、hs-CRP以及不良反应发生率均低于对照组,LVEF高于对照组(P<0.05)。结论替格瑞洛联合阿司匹林可明显改善AMI患者左心室功能,减轻机体炎性反应,降低不良反应发生率。Objective To explore the application effect of ticagrelor combined with aspirin in patients with acute myocardial infarction(AMI).Methods 120 AMI patients were randomly divided into two groups.The control group was treated with clopidogrel combined with aspirin,and the observation group was treated with ticagrelor combined with aspirin.The left ventricular function indicators,levels of inflammatory factors,and adverse reactions were compared between the two groups.Results After treatment,the LVEDD,IL-6,TNF-α,hs-CRP,and incidence of adverse reactions of the observation group were lower than those of the control group,and LVEF was higher than that of the control group(P<0.05).Conclusions Ticagrelor combined with aspirin can obviously improve the left ventricular function of AMI patients,relieve body's inflammatory response,and reduce the incidence of adverse reactions.

关 键 词：替格瑞洛 阿司匹林 急性心肌梗死 左心室功能 炎性因子 

分 类 号：R542.22[医药卫生—心血管疾病]