恶性肿瘤患者术后恐惧复发影响因素的meta分析  

Influencing factors of postoperative fear recurrence in patients with malignant tumor:a meta-analysis

作　　者：张文惠 史加海[2] 秦毅[2] ZHANG Wenhui;SHI Jiahai;QIN Yi(Medical School of Nantong University,Nantong,Jiangsu 226000,China;Affiliated Hospital of Nantong University,Nantong,Jiangsu 226000,China)

机构地区：[1]南通大学医学院,江苏南通226000 [2]南通大学附属医院,江苏南通226000

出　　处：《重庆医学》2023年第4期545-551,557,共8页Chongqing medicine

基　　金：国家自然科学基金项目(81770266)。

摘　　要：目的评价恶性肿瘤患者术后恐惧复发的影响因素。方法计算机检索Web of Science、PubMed、Embase、CINAHL、Cochrane Library、中国知网、万方、中国生物医学文献数据库、维普等数据库中关于恶性肿瘤患者术后恐惧复发的研究。采用RevMan 5.4进行分析。结果最终纳入文献21篇,共4620例患者,纳入19项危险因素。meta分析显示,年轻[比值比(OR)=0.66,95%置信区间(95%CI)为0.49~0.90,P<0.01]、家庭人均月收入低(OR=0.41,95%CI=0.26~0.65,P<0.001)、有家族史(OR=7.43,95%CI=1.38~39.94,P<0.05)、肿瘤分期高(OR=2.67,95%CI=1.86~3.83,P<0.001)、心理辅导需求高(OR=3.05,95%CI=1.84~5.04,P<0.001)、焦虑(OR=1.28,95%CI=1.04~1.58,P<0.05)、疾病感知严重(OR=1.11,95%CI=1.05~1.18,P<0.001)及希望水平低(OR=0.80,95%CI=0.73~0.89,P<0.001)是恶性肿瘤患者术后恐惧复发的重要影响因素。结论年轻、家庭人均月收入较低、焦虑等患者术后恐惧复发的可能性较大,关于文化程度、社会支持等的预测价值,现有证据尚不充分。Objective To evaluate the influencing factors of postoperative fear recurrence in patients with malignant tumor.Methods The research on postoperative fear recurrence in patients with malignant tumor was searched by computer in Web of Science,PubMed,Embase,CINAHL,Cochrane Library,China HowNet,Wanfang,China Biomedical Literature Database,VIP and other databases.RevMan 5.4 was used for analysis.Results In the end,a total of 21 articles with 4620 patients were included,and 19 risk factors were included.Meta-analysis showed that young(OR=0.66,95%CI=0.49-0.90,P<0.01)low-per capita monthly income(OR=0.41,95%CI=0.26-0.65,P<0.001)family history(OR=7.43,95%CI=1.38-39.94,P<0.05),high tumor staging(OR=2.67,95%CI=1.86-3.83,P<0.001),high demand for psychological counseling(OR=3.05,95%CI=1.84-5.04,P<0.001),anxiety(OR=1.28,95%CI=1.04-1.58,P<0.05),serious disease perception(OR=1.11,95%CI=1.05-1.18,P<0.001),and low hope level(OR=0.80,95%CI=0.73-0.89,P<0.001)were important influencing factors for postoperative fear recurrence of patients with malignant tumors.Conclusion Young,low family income,anxiety and other patients are more likely to have postoperative fear recurrence.The existing evidence about the predictive value of education and social support is not sufficient.

关 键 词：恶性肿瘤 术后 恐惧复发 影响因素 META分析 

分 类 号：R473[医药卫生—护理学]