1例特重度烧伤患者万古霉素浓度与药学监护  

A Case of Pharmaceutical Care Based on Plasma Concentration Monitoring of Vancomycin with Extremely Severe Burn Patient

作　　者：刘瑶 明丹丹 LIU Yao;MING Dandan(Department of Pharmacy,The Fifth Affiliated Hospital of Sun-Yat Sen University,Zhuhai,Guangdong 519000,China)

机构地区：[1]中山大学附属第五医院药学部,广东珠海519000

出　　处：《今日药学》2022年第11期863-866,共4页Pharmacy Today

摘　　要：目的为特重度烧伤患者的万古霉素剂量调整提供参考。方法以1例特重度烧伤患者抗感染治疗及药学监护为例,探讨万古霉素等抗菌药物治疗的有效性及合理性,同时从患者病理生理状态及药代动力学等角度分析万古霉素血药浓度异常值的影响因素。结果患者经抗感染治疗后,万古霉素血药浓度未达标,但临床治疗有效。结论建议特重度烧伤患者万古霉素剂量调整应综合患者情况并密切监测万古霉素血药浓度。OBJECTIVE To provide reference for vancomycin dose adjustment in severe burn patients.METHODS Taking the anti-infective treatment and pharmaceutical care of a patient with extremely severe burn as an example,the effectiveness and rationality of vancomycin and other antibacterial drugs were discussed and the influencing factors of abnormal vancomycin plasma concentration from the perspectives of pathophysiological state and pharmacokinetics of patients were analyzed.RESULTS After the anti-infective treatment,the plasma concentration of vancomycin did not reach the standard,but the clinical treatment was effective.CONCLUSION The dose adjustment of vancomycin in patients with extremely severe burns should be based on the individual situation and monitor the concentration frequently.

关 键 词：万古霉素 特重度烧伤 血药浓度监测 药学监护 

分 类 号：R95[医药卫生—药学]