2022年免疫学研究热点回眸  

Hotspots of immunology in 2022:A review

作　　者：黄波[1] HUANG Bo(Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences,Beijing 100730,China)

机构地区：[1]中国医学科学院基础医学研究所,北京100730

出　　处：《科技导报》2023年第1期124-130,共7页Science & Technology Review

摘　　要：全球科学家在新冠病毒疫情的巨大挑战中从未停止免疫学研究的步伐,2022年免疫学仍然取得了长足进展。概述了2022年免疫学研究的热点及进展,包括T细胞记忆、干性及耗竭分化的深入探究、新的免疫检查点和免疫细胞亚群的发现、通过神经内分泌及代谢途径调控免疫以及免疫治疗新策略的探索。Global scientists have not stopped the pace of immunological research to meet the great challenge of the COVID-19 pandemic.In the past 2022,immunology made significant progress.This review highlights a few breakthroughs,including the in-depth exploration of T cell memory,stemness and exhaustion,the discovery of new immune checkpoints and immune cell subsets,exploration of immune regulation through neuroendocrine and metabolic pathways,and exploration of new strategies for immunotherapy.

关 键 词：免疫记忆 T细胞耗竭 干性样T细胞 CAR-T 神经内分泌和代谢调控 

分 类 号：R392[医药卫生—免疫学]