高效液相色谱法同时测定复合膜袋中苯代三聚氰胺及二种二苯甲酮化合物的含量  

Simultaneous Determination of Benzonquanmine and Two Benzophenone Compounds in Composite Membrane Bags by High-performance Liquid Chromatography

作　　者：张涛 曾莉 林黛琴 聂绍丽 Zhang Tao;Zeng Li;Lin Dai-qin;Nie Shao-li(Jiangxi General Institute of Testing and Certification Institute of Inspection and Testing for Industrial Products,Nanchang Jiangxi 330052,China)

机构地区：[1]江西省检验检测认证总院工业产品检验检测院,江西南昌330052

出　　处：《江西化工》2023年第1期20-23,共4页Jiangxi Chemical Industry

基　　金：江西省市场监督管理局科技计划项目(GSJK202013)资助。

摘　　要：本文建立了高效液相色谱法同时测定复合膜袋中苯代三聚氰胺、2,4-二羟基二苯甲酮和2-羟基-4-甲氧基二苯甲酮残留量的方法。试样剪成小于2 mm的碎片,经甲醇超声提取,氮气浓缩至干,再用2 m L流动相超声溶解,经0.45μm滤膜过滤后,采用液相色谱(配PDA检测器)进行检测,外标法定量。研究表明:在0.05~10.0 mg/L的范围内,各标准物质线性关系良好,相关系数(r)均大于0.9995,方法检出限低,回收率在88.60%~112.32%,相对标准偏差(RSD)在0.09%~3.05%之间,方法精密度较好。该方法简便快捷,结果准确可靠,时效性高。A High-performance liquid chromatography method was developed for the simultaneous determination of the residues of benzonquanmine, 2,4-dihydroxybenzophenone and 2-hydroxy-4-methoxybenzophenone in composite membrane bags. The sample was cut into fragments smaller than 2 mm, extracted by ultrasonic with methanol,concentrated to dry with nitrogen, then dissolved by ultrasonic with 2 mL mobile phase, filtered by 0.45 μm filter membrane, detected by liquid chromatography(with PDA detector) and quantified by external standard method. The results showed that in the concentration range of 0.05~10.0 mg/L, the linear relationship of the standard substances were good, and the correlation coefficient(R) were greater than 0.9995. The detection limit of the method were low,and the recoveries ranged from 88.60% to 112.32% with the relative standard deviation(RSD) of 0.09% ~ 3.05%, and the precision of the method were good. The method is simple, rapid, accurate and reliable with high timeliness.

关 键 词：复合膜袋 苯代三聚氰胺 2 4-二羟基二苯甲酮 2-羟基-4-甲氧基二苯甲酮 残留量 

分 类 号：O657[理学—分析化学]