炎症性肠病患者疲乏影响因素的Meta分析  

作　　者：蔡媛媛 谢舒 周英淑仪 裘秀月[1] 

机构地区：[1]浙江中医药大学护理学院,310053

出　　处：《浙江临床医学》2023年第1期83-86,共4页Zhejiang Clinical Medical Journal

基　　金：浙江省中医药科技计划项目(2022ZB092)。

摘　　要：目的系统评价炎症性肠病患者疲乏的影响因素。方法计算机检索中国知网(CNKI)、万方数据库、中国生物医学文献数据库(CBM)、维普(VIP)、PubMed、EMbase、MedLine、Cochrane Library。检索从建库至2021年2月所有有关炎症性肠病患者疲乏影响因素的研究。采用RevMan 5.3软件进行Meta分析。结果最终纳入7篇文献,共1895例患者。Meta分析结果显示:女性[OR:3.67,95%CI(2.31~5.83),P<0.001]、焦虑[OR:1.71,95%CI(1.45~2.02),P<0.001]、抑郁[OR:1.68,95%CI(1.32~2.15),P<0.001]、疾病活动期[OR:1.49,95%CI(1.09~2.03),P=0.01]与炎症性肠病患者疲乏症状有统计学意义,而贫血与疲乏症状无统计学意义(P>0.05)。结论性别、焦虑、抑郁、疾病活动期是炎症性肠病患者疲乏的影响因素。Objective To systematically evaluate the influencing factors of fatigue in patients with inflammatory bowel disease(IBD).Methods CNKI,Wanfang Database,CBM,VIP,PubMed,EMbase,MedLine and Cochrane Library were searched by computer.All studies on the influencing factors of fatigue in patients with IBD from the establishment of the database to February 2021 were retrieved.RevMan 5.3 software was used for meta-analysis.Results A total of 7 literatures were included,including 1895 patients.The results of meta-analysis showed that female[OR:3.67,95%CI(2.31~5.83),P<0.001],anxiety[OR:1.71,95%CI(1.45~2.02),P<0.001],depression[OR:1.68,95%CI(1.32~2.15),P<0.001],disease activity stage[OR:1.49,95%CI(1.09~2.03),P=0.01]were statistically significant with fatigue symptoms in IBD patients,but anemia was not significantly correlated with fatigue(P>0.05).Conclusion Gender,anxiety,depression and active stage of disease are the influencing factors of fatigue in patients with IBD.

关 键 词：炎症性肠病 疲乏 影响因素 META分析 

分 类 号：R47[医药卫生—护理学]