磁共振参数定量技术在心肌受累疾患中的应用及研究进展  

Application and research progress of magnetic resonance parameter quantitative technique in myocardial involvement diseases

作　　者：阿巴斯江·阿地力 李杉 齐海成 刘倩 栗岩 邢艳 ABASIJIANG·Adili;LI Shan;QI Haicheng;LIU Qian;LI Yan;XING Yan(Department of Radiology,Affiliated First Hospital of Xinjiang Medical University,Urumqi 830011,China)

机构地区：[1]新疆医科大学第一附属医院影像中心,乌鲁木齐830011

出　　处：《磁共振成像》2023年第2期179-185,共7页Chinese Journal of Magnetic Resonance Imaging

基　　金：国家自然科学基金(编号:82160334);自治区区域协同创新专项(科技援疆计划)(编号:2021E02067)。

摘　　要：心肌受累疾患病种较多,包括原发性及继发性改变,由于其伴心功能受损而严重危及患者生命,因此早期诊断并干预心肌改变显得尤为重要。心脏磁共振(cardiac magnetic resonance,CMR)广泛应用于与心血管疾病相关的各种医学领域。近年来快速的技术创新促进了CMR成像新技术的发展。参数定量技术如纵向弛豫时间定量成像(T1 mapping)、横向弛豫时间定量成像(T2 mapping)提供了一种非侵入性检查手段,可量化心肌疾病中的组织改变。这些变化主要包括心肌纤维化、心肌水肿伴细胞内和/或细胞外水增加、心肌内出血等病理改变。T1 mapping和T2 mapping不仅被认为是诊断心肌病的可靠生物标志物,而且被认为是治疗监测和预后评估中可靠的影像学参数。本文就参数定量技术评估心肌组织方面的应用及研究进展予以综述,目的是阐述参数定量技术如何早期和精准识别异常心肌,同时提出了存在的问题及未来研究思路,为该技术的研究提供参考。There are many kinds of myocardial involvement diseases,including primary and secondary changes.Because of its accompanying cardiac function damage,it seriously endangers the life of patients,early diagnosis and intervention of myocardial changes is particularly important.Cardiac magnetic resonance(CMR)is widely used in various medical fields related to cardiovascular diseases.In recent years,rapid technological innovation has led to new CMR imaging technology development.Parametric quantitative techniques,such as longitudinal relaxation time quantitative imaging(T1 mapping)and transverse relaxation time quantitative imaging(T2 mapping),provide a non-invasive examination method to quantify tissue changes in myocardial disease.These changes mainly include myocardial fibrosis,myocardial edema with increased intracellular and/or extracellular water,and myocardial hemorrhage and other pathological changes.T1 mapping and T2 mapping are not only considered to be reliable biomarkers for the diagnosis of cardiomyopathy but are also considered to a reliable imaging parameter in treatment monitoring and prognosis evaluation.This article reviews application of parametric quantitative techniques and research progress in evaluating myocardial tissue.The purpose is to describe how the parameter quantitative technology can identify abnormal myocardium early and accurately,and put forward the existing problems and future research ideas to provide references for the research of this technology.

关 键 词：心脏 磁共振成像 T1 mapping T2 mapping 定量评估 细胞外体积分数 

分 类 号：R445.2[医药卫生—影像医学与核医学] R541[医药卫生—诊断学]