腹腔内热灌注化疗在胃癌中的应用  

Application of intraperitoneal hyperthermic perfusion chemotherapy in gastric cancer

作　　者：周悦 齐梅 周宇轩 方盛泉[1] Yue Zhou;Mei Qi;Yu-Xuan Zhou;Sheng-Quan Fang(Department of Gastroenterology,Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese medicine,Shanghai 200437,China)

机构地区：[1]上海中医药大学附属岳阳中西医结合医院消化内科,上海市200437

出　　处：《世界华人消化杂志》2023年第1期1-7,共7页World Chinese Journal of Digestology

基　　金：上海市自然基金,No.20ZR145930;上海申康中心临床培育项目,No.SHD12018X30;上海中医药大学附属岳阳中西医结合医院院级重点基金,No.2019YY201;上海中医药大学附属岳阳中西医结合医院院级特别基金,No.2021yygm06。

摘　　要：胃癌是我国常见恶性肿瘤之一.腹腔热灌注化疗是一种结合腹腔灌注、热疗和化疗的综合疗法,在胃癌腹膜(或腹腔内)转移中具有较好疗效.近年来,随着技术的不断进步及研究的不断深入,腹腔热灌注化疗技术应用范围更加广泛.本文就腹腔热灌注化疗技术及其在胃癌中的应用人群、常用药物、安全性进行论述并提出展望.Gastric cancer is one of the most common malignant tumors in China.Intraperitoneal hyperthermic perfusion chemotherapy is a comprehensive therapy that combines intraperitoneal perfusion,hyperthermia,and chemotherapy.It has a good curative effect in peritoneal metastasis of gastric cancer.In recent years,with the continuous progress of technology and the deepening of research,the scope of application of intraperitoneal hyperthermic perfusion chemotherapy is more extensive.In this paper,we discuss intraperitoneal hyperthermic perfusion chemotherapy with regard to its application in gastric cancer,commonly used drugs,safety,and prospects.

关 键 词：胃癌 腹腔转移 腹腔热灌注化疗 作用机制 临床应用 NIPS 化疗药物 

分 类 号：R735.2[医药卫生—肿瘤]