GDM孕妇孕晚期脐动脉血流S/D值与胎儿窘迫的关系分析  

Analysis of S/D value of umbilical artery blood flow in late pregnancy of GDM pregnant women and fetal distress

作　　者：王月菊 孙玉敏 WANG Yueju;SUN Yumin(Department of Obstetrics and Gynecology,The First People’s Hospital Daishan,Zhoushan 316200,China)

机构地区：[1]岱山县第一人民医院妇产科,浙江舟山316200

出　　处：《健康研究》2023年第1期91-94,共4页Health Research

摘　　要：目的探讨妊娠糖尿病(gestational diabetes mellitus,GDM)孕妇孕晚期脐动脉血流收缩期最大血流速度/舒张期血流速度(S/D)值与胎儿宫内窘迫的相关性,为临床预防胎儿宫内窘迫提供参考依据。方法回顾分析100例GDM孕妇的临床资料,另选取同期在我院生产的100例健康孕妇作为对照组。比较2组孕妇孕晚期脐动脉血流S/D值,采用受试者工作特征曲线(ROC)评估脐动脉血流S/D值与胎儿宫内窘迫的关系。结果孕晚期,研究组脐动脉血流S/D值(2.91±0.35)高于对照组(2.62±0.29),差异有统计学意义(t=6.380,P<0.001)。脐动脉血流S/D值在≤2.50和2.50~2.75范围内的胎儿宫内窘迫发生率比较,2组间差异无统计学意义(P>0.05);S/D值在2.76~3.0和>3.0范围内的胎儿宫内窘迫发生率,研究组高于对照组,差异有统计学意义(P<0.05)。孕妇孕晚期脐动脉血流S/D值预测胎儿宫内窘迫的ROC曲线下面积为0.760,当脐动脉血流S/D值为2.85时,约登指数最大为0.504,对应的灵敏度和特异性分别为0.745、0.759。结论与健康孕妇相比,GDM孕妇孕晚期脐动脉血流S/D值与胎儿宫内窘迫发生风险均明显增高,脐动脉血流S/D值可作为胎儿宫内窘迫的预测指标。Objective To investigate the correlation between the maximum systolic blood flow velocity/diastolic blood flow velocity(S/D)of umbilical artery blood flow in late pregnancy of pregnant women with gestational diabetes mellitus(GDM)and fetal distress so as toprovide reference for clinical prevention of fetal distress.Methods The clinical data of 100 pregnant women with GDM were retrospectively analyzed,and 100 healthy pregnant women delivered in our hospital in the same period were selected as the control group.The S/D value of umbilical artery blood flow in late pregnancy was compared between the two groups.The relationship between S/D value of umbilical artery blood flow and fetal distress was evaluated by receiver operating characteristic curve(ROC).Results In late pregnancy,the S/D value of umbilical artery blood flow in the study group(2.91±0.35)was higher than that in the control group(2.62±0.29),and the difference was statistically significant(t=6.380,P<0.001).There was no significant difference between the two groups in the incidence of fetal distress when the S/D value of umbilical artery blood flow was≤2.50 and 2.50-2.75(P>0.05).The incidence of fetal distress in the study group was higher than that in the control group when the S/D value was in the range of 2.76-3.0 and>3.0,and the difference was statistically significant(P<0.05).The area under ROC curve of umbilical artery blood flow S/D value in late pregnancy to predict fetal distress was 0.760.When the S/D value of umbilical artery blood flowwas 2.85,the maximum Jordan index was 0.504,and the corresponding sensitivity and specificity were 0.745 and 0.759,respectively.Conclusions Compared with healthy pregnant women,the S/D value of umbilical artery blood flow in late pregnancy of GDM pregnant women and the risk of fetal distress are significantly higher.The S/D value of umbilical artery blood flow can be used as a predictor of fetal distress.

关 键 词：妊娠糖尿病 胎儿宫内窘迫 脐动脉血流 彩色多普勒超声 预测 

分 类 号：R71[医药卫生—妇产科学]