西澳菲斯特农场赤桉蜂蜜促进感染创面愈合作用研究  

Study on the Effect of Fewster’s Farm Jarrah Honey on the Healing of Infected Wounds

作　　者：陈艳欣 林韦康 Chen Yanxin;Lin Weikang(Wang Shuhe(Zhengzhou)Biopharmaceutical Engineering Co.,Ltd.,Zhengzhou,China;Wang Shuhe Biomedical(Wuhan)Co.,Ltd.,Wuhan,China)

机构地区：[1]王叔和(郑州)生物制药工程有限公司,河南郑州 [2]王叔和生物医药(武汉)有限公司,湖北武汉

出　　处：《科学技术创新》2023年第4期41-44,共4页Scientific and Technological Innovation

摘　　要：目的:评价西澳菲斯特农场赤桉蜂蜜(Fewster’s Farm jarrah honey,FFJH)对感染创面愈合的影响。方法:通过CCK-8和体外抑菌实验,研究了FFJH对人表皮永生化细胞(Human Diploid Fibroblast,HDF)增殖的影响和体外抗金黄色葡萄球菌和大肠杆菌的活性;通过建立SD大鼠感染创面模型,评估了FFJH对促进感染创面愈合的效果和抑制创面区域金黄色葡萄球菌增长的能力。结果:FFJH在体外可以促进HDF的增殖、抑制金黄色葡萄球菌和大肠杆菌的增殖;体内效果表明,FFJH可以有效抑制创面区域金黄色葡萄球菌的增长并加速感染创面的愈合。结论:西澳菲斯特农场赤桉蜂蜜可显著促进感染创面愈合。Objective: To evaluate the effect of Fewster’s Farm jarrah honey(FFJH) on the healing of infected wounds. Methods: The effect of FFJH on the proliferation of human dermal fibroblast(HDF) cells and the activities against Staphylococcus aureus and Escherichia coli in vitro were evaluated by CCK-8 and in vitro bacteriostasis experiments. The effect of FFJH on promoting the healing of infected wounds and inhibiting the growth of Staphylococcus aureus in the wound area were evaluated by establishing an infected wound model of SD rats. Results: FFJH could promote the proliferation of HDF and inhibit the proliferation of Staphylococcus aureus and Escherichia coli in vitro;The in vivo effect shows that FFJH can effectively inhibit the growth of Staphylococcus aureus in the wound area and accelerate the healing of infected wounds.Conclusion: FFJH can significantly promote the healing of infected wounds.

关 键 词：西澳菲斯特农场赤桉蜂蜜 抗菌 感染性创面 创面修复 

分 类 号：R95[医药卫生—药学]