鼻腔呼吸道上皮腺瘤样错构瘤1例并文献复习  

Respiratory epithelial adenomatoid hamartoma in the nasal cavity:a case report and literature review

作　　者：岑艳芳 伍映芳 胡玉莹 孔喆 梁艳 李兴亚 夏纪严 CEN Yanfang;WU Yingfang;HU Yuying;KONG Zhe;LIANG Yan;LI Xingya;XIA Jiyan(The Second Clinical College of Guangzhou University of Chinese Medicine,Guangzhou 510403,Guangdong,China;Department of Otolaryngology Head and Neck,The Second Affiliated Hospital of Guangzhou University of Chinese Medicine/Guangdong Provincial Hospital of Chinese Medicine,Guangzhou 510006,Guangdong,China;Department of Pathology,The Second Affiliated Hospital of Guangzhou University of Chinese Medicine/Guangdong Provincial Hospital of Chinese Medicine,Guangzhou 510006,Guangdong,China)

机构地区：[1]广州中医药大学第二临床医学院,广东广州510403 [2]广州中医药大学第二附属医院/广东省中医院耳鼻咽喉头颈科,广东广州510006 [3]广州中医药大学第二附属医院/广东省中医院病理科,广东广州510006

出　　处：《山东大学耳鼻喉眼学报》2023年第1期30-34,55,共6页Journal of Otolaryngology and Ophthalmology of Shandong University

摘　　要：目的 探讨鼻腔呼吸上皮性腺瘤样错构瘤(REAH)的临床、影像、病理学特征及治疗。方法 分析1例鼻腔REAH患者的临床资料并复习相关文献进行总结。结果 鼻腔REAH临床表现常以鼻塞、嗅觉减退为主。影像学方面,嗅裂增宽>10 mm是本病在CT上的特征性表现。本病确诊主要依靠病理检查,其显微镜下特点是大量内衬呼吸道纤毛上皮的腺体显著增生。结论 鼻腔REAH临床表现无特异性,因而影像学及组织学检查对本病的早期诊断尤其重要。内镜下切除肿瘤是本病的最佳治疗手段。Objective To explore the clinical, imaging, pathological features and treatment of nasal respiratory epithelial adenomatous hamartoma(REAH). Methods We report the case of a patient with REAH in the nasal cavity and review prior cases of REAH in the nasal cavity published in the literature. Results The most frequent symptoms of REAH in the nasal cavity are nasal obstruction and olfactory impairment. In terms of imaging, olfactory cleft widening greater than 10 mm on computed tomography is characteristic of REAH. The diagnosis of REAH relies mainly on pathology;this malformationis characterized by a prominent glandular proliferation lined by ciliated respiratory epithelial cells. Conclusion The clinical symptoms of REAH are nonspecific. Therefore, imaging and histopathological examinations are especially important for its early diagnosis. Endoscopic resection is the treatment of choice for REAH.

关 键 词：呼吸道上皮腺瘤样错构瘤 鼻腔 错构瘤 嗅裂 病理活检 

分 类 号：R765.2[医药卫生—耳鼻咽喉科] R739.62[医药卫生—临床医学]