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作 者:徐忠友 XU Zhong-you(The Second Department of Surgery,Dexing People's Hospital,Dexing 334200,Jiangxi,China)
出 处:《医学信息》2023年第3期132-135,共4页Journal of Medical Information
摘 要:目的研究标准化手术时机选择对急性粘连性肠梗阻患者进行手术治疗的效果。方法选取2016年3月-2021年7月在我院诊治的72例急性粘连性肠梗阻患者为研究对象,采用随机数字表法分为对照组和观察组,各36例。对照组采用常规手术时机进行手术治疗选择,观察组采用标准化手术时机选择手术治疗。比较两组治疗效果、胃肠功能恢复指标、炎性细胞因子水平、急性生理与慢性健康评分(APACHE-Ⅱ评分)、并发症发生率以及复发率。结果观察组治疗总有效率为94.44%,高于对照组的80.55%(P<0.05);观察组腹痛消失、肠鸣音消失、术后肛门恢复排气、术后排便时间均短于对照组(P<0.05);观察组肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、C反应蛋白(CRP)水平均低于对照组(P<0.05);两组术后APACHE-Ⅱ评分均低于术前,且观察组低于对照组(P<0.05);观察组并发症发生率为8.33%,低于对照组的19.44%(P<0.05);随访3个月,观察组复发率为5.56%,低于对照组的13.89%(P<0.05)。结论标准化手术时机选择对急性粘连性肠梗阻患者进行手术治疗效果确切,可提高治疗总有效率,快速减轻临床症状,抑制炎症反应,且可降低并发症发生率和复发率,具有相对良好的手术治疗效果,值得临床应用。Objective To study the effect of standardized operation timing on surgical treatment of patients with acute adhesive intestinal obstruction.Methods A total of 72 patients with acute adhesive intestinal obstruction diagnosed and treated in our hospital from March 2016 to July 2021 were selected as the research objects.They were divided into control group and observation group by random number table method,with 36 cases in each group.The control group was treated with conventional surgical timing for surgical treatment,and the observation group was treated with standardized surgical timing for surgical treatment.The therapeutic effect,gastrointestinal function recovery index,inflammatory cytokine level,acute physiology and chronic health score(APACHE-Ⅱscore),complication rate and recurrence rate were compared between the two groups.Results The total effective rate of treatment in the observation group was 94.44%,which was higher than 80.55%in the control group(P<0.05).The time of abdominal pain disappearance,bowel sound disappearance,postoperative anal exhaust recovery and postoperative defecation in the observation group were shorter than those in the control group(P<0.05).The levels of tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),C-reactive protein(CRP)in the observation group were lower than those in the control group(P<0.05).The APACHE-Ⅱscores of the two groups were lower than those before operation,and those in the observation group were lower than those in the control group(P<0.05).The incidence of complications in the observation group was 8.33%,which was lower than 19.44%in the control group(P<0.05).After 3 months of follow-up,the recurrence rate of the observation group was 5.56%,which was lower than 13.89%of the control group(P<0.05).Conclusion Standardized surgical timing is effective in surgical treatment of patients with acute adhesive intestinal obstruction,which can improve the total effective rate of treatment,quickly reduce clinical symptoms,inhibit inflammatory response,and reduce the
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