新型降糖药物治疗2型糖尿病的研究进展  

Research progress of new hypoglycemic drugs in the treatment of type 2 diabetes

作　　者：杨燕 卓见 申红霞 韩瑞敏 王珍 王德峰[2] YANG Yan;ZHUO Jian;SHEN Hongxia;HAN Ruimin;WANG Zhen;WANG Defeng(Clinical Medical College of Hebei University of Engi-neering,Handan 056000,China;不详)

机构地区：[1]河北工程大学临床医学院,河北邯郸056000 [2]河北工程大学附属医院内分泌科,河北邯郸056000

出　　处：《实用医学杂志》2023年第2期153-157,共5页The Journal of Practical Medicine

基　　金：河北省财政厅资助临床医学优秀人才项目基金(编号:[2020]23号)。

摘　　要：近年来糖尿病的患病率和死亡率迅速增加。关于缓解2型糖尿病(type 2 diabetes mellitus,T2DM)的新靶点的药物数见不鲜,目前有12个不同类别的抗糖尿病药物可供选择,其通过糖尿病的发生机制的各个环节提出了各种治疗措施,新型降糖药物与传统药物相比更具安全性、有效性,且对心肾具有保护作用,延缓糖尿病并发症。本文对当前已上市治疗T2DM新靶点药物进行综述,以期为T2DM临床治疗提供指导。The morbidity and mortality of diabetes have increased rapidly in recent years.The drugs aiming to act on new targets to control type 2 diabetes mellitus(T2DM)is not uncommon.At present,12 different types of anti-diabetic drugs are available to be used,offering various treatment measures through all aspects of the mechanism of diabetes.As compared with traditional drugs,new hypoglycemic drugs are safer and more effective,and have a protective effect on heart and kidney,delaying the occurrence of diabetic complications.This article reviews the current drugs acting at new targets for the treatment of T2DM in order to provide guidance for clinical treatment of T2DM.

关 键 词：2型糖尿病 新型降糖药物 新靶点 综述 

分 类 号：R587.1[医药卫生—内分泌]