CT薄层扫描在非结核分枝杆菌治疗过程的应用价值  

The Application Value of CT Thin-section Scanning in the Treatment of Non-tuberculous Mycobacteria

作　　者：李蔚宇[1] 袁光峰 唐城 LI Weiyu;YUAN Guangfeng;TANG Cheng(Guangzhou Chest Hospital,Guangzhou,Guangdong,510095)

机构地区：[1]广州市胸科医院,广东广州510095

出　　处：《智慧健康》2022年第34期1-5,9,共6页Smart Healthcare

摘　　要：目的探讨CT薄层扫描在非结核分枝杆菌(non-tuberculous mycobacteriosis,NTM)治疗过程中的应用价值。方法选择2019年1月-2020年6月NTM患者150例作为研究对象,所有患者均给予药物治疗,包括克拉霉素、利福平、乙胺丁醇及阿米卡星等,连续治疗6~18个月。患者治疗前、后均行CT薄层扫描,分析患者不同性别、年龄下CT薄层扫描征象及患者治疗前后CT薄层扫描变化,分析其治疗指导价值。结果150例NTM患者男性与女性CT薄层扫描各征象比较,差异无统计学意义(P>0.05);CT薄层扫描征象排在前三位的分别为:小叶中心结节、斑片状及支气管壁增厚,分别占95.33%、72.67%和59.33%;≥60岁患者斑片状、气管壁增厚、不确定结节、小叶实变、支气管扩张高于<60岁患者CT薄层扫描各征象比较,差异有统计学意义(P<0.05);150例NTM患者均经药物治疗,病灶吸收明显,与治疗前相比肺功能得到明显改良,但是部分患者出现不同程度胸膜增厚粘连。结论CT薄层扫描用于NTM患者能指导临床治疗,且不同性别CT薄层扫描征象无明显差异,而年龄较大人群CT薄层扫描征象更明显,可根据影像学检查结果指导治疗。Objective To explore the application value of CT thin-section scanning in the treatment of non-tuberculous mycobacteriosis(NTM).Methods A total of 150 patients with NTM disease from January 2019 to June 2020 were selected as the subjects.All patients were given drug treatment,including:clarithromycin,rifampicin,ethambutol and amikacin,etc.,continuous treatment for 6~18 months.The patients underwent CT thin-slice scan before and after treatment.The CT thinslice scan signs of patients with different genders and ages and the changes of CT thin-slice scan before and after treatment were analyzed,and their therapeutic guidance value was analyzed.Results There was no statistical significance in CT thin-section scans between men and women in 150 NTM patients(P>0.05).The top three CT thin-section scan signs were:centrilobular nodules,patches and bronchial wall thickening,accounting for 95.33%,72.67%and 59.33%respectively;patchy,tracheal wall thickening,indeterminate nodules,lobular consolidation,and bronchiectasis in patients aged≥60 years were higher than those in patients aged<60 years(P<0.05).After drug treatment,150 NTM patients had obvious absorption of lesions,and lung function was significantly improved compared with before treatment,but some patients had different degrees of thick pleural adhesions.Conclusion CT thin-section scanning can guide clinical treatment in the treatment of NTM patients,and there is no significant difference in CT thin-section scanning signs between different genders,while the CT thinsection scanning signs are more obvious in older people,which can be guided according to the results of imaging examinations treat.

关 键 词：CT薄层扫描 非结核分枝杆菌 药物治疗 CT征象 指导价值 

分 类 号：R446.5[医药卫生—诊断学]