不同浓度局部氧疗联合负压封闭引流技术对下肢创伤性皮肤缺损创面愈合的影响  

Influence of different concentration of local oxygen therapy combined with vacuum sealing drainage technology on wound healing of lower extremity traumatic skin defect

作　　者：顾翠霞 陈雯 王月华 GU Cuixia;CHEN Wen;WANG Yuehua(Department of Orthopedics,Suzhou Science and Technology City Hospital,Jiangsu Province,Suzhou215153,China)

机构地区：[1]江苏省苏州科技城医院骨科,江苏苏州215153

出　　处：《中国医药导报》2023年第4期104-107,共4页China Medical Herald

基　　金：江苏省科技计划项目(BK20181113);南京医科大学科技发展基金一般项目(NMUB2020247)。

摘　　要：目的探讨不同浓度局部氧疗联合负压封闭引流(VSD)技术对下肢创伤皮肤缺损创面愈合的影响。方法选择2020年3月至2021年2月江苏省苏州科技城医院收治的下肢创伤皮肤软组织缺损患者160例为研究对象,采用分层随机法将其分为A、B、C、D组,各40例。A组给予VSD治疗,B组给予1 L/min持续氧疗联合VSD,C组给予3 L/min持续氧疗联合VSD,D组给予5 L/min持续氧疗联合VSD。比较四组治疗7 d后的创面情况、创面植皮时间、创面愈合时间、住院时间及不良反应发生情况。结果治疗7 d后,B、C、D组肉芽组织覆盖率均高于A组,C、D组高于B组,D组高于C组(P<0.05)。B、C、D组创面植皮时间、创面愈合时间、住院时间均短于A组,C、D组短于B组(P<0.05)。两组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论局部氧疗联合VSD能够促进下肢创伤性皮肤缺损创面生长,缩短治疗周期,但要注意预防高浓度氧疗可能导致的不良反应。Objective To investigate the Influence of different concentration of local oxygen therapy combined with vacuum sealing drainage(VSD)technology on wound healing of lower extremity traumatic skin defect.Methods A total of 160 patients with lower extremity traumatic skin and soft tissue defects admitted to Suzhou Science and Technology City Hospital of Jiangsu Province from March 2020 to February 2021 were selected as the study objects.Stratified randomized method was used to divide them into groups A,B,C,and D,with 40 cases each.Group A was given VSD,group B was given 1 L/min continuous oxygen therapy combined with VSD,group C was given 3 L/min continuous oxygen therapy combined with VSD,and group D was given 5 L/min continuous oxygen therapy combined with VSD.The wound condition,wound skin grafting time,wound healing time,hospital stay time,and the occurrence of adverse reactions were compared between the four groups after seven days of treatment.Results After seven days of treatment,granulation tissue coverage in groups B,C,and D was higher than those in group A,groups C and D were higher than group B,and group D was higher than group C(P<0.05).The wound skin grafting time,wound healing time,and hospital stay in groups B,C,and D were shorter than those in group A,groups C and D were shorter than group B(P<0.05).There was no significant difference in the total incidence of adverse reactions among four groups(P>0.05).Conclusion Local oxygen therapy combined with VSD can promote the growth of lower limb traumatic skin defect wounds,shorten the treatment cycle,but attention should be paid to prevent the adverse reactions that may be caused by high concentration oxygen therapy.

关 键 词：下肢 皮肤软组织缺损 负压封闭引流 局部氧疗 浓度 创面愈合 

分 类 号：R473.6[医药卫生—护理学]