芒果苷调节糖脂代谢作用的研究进展  

Research progress of action on the mangiferin regulating glycolipid metabolism

作　　者：徐亚慧 殷建忠 阮锡宇 赵婷 张俏 XU Yahui;YIN Jianzhong;RUAN Xiyu;ZHAO Ting;ZHANG Qiao(School of Public Health,Kunming Medical University,Yunnan Province,Kunming650500,China;Baoshan College of Traditional Chinese Medicine,Yunnan Province,Baoshan678000,China)

机构地区：[1]昆明医科大学公共卫生学院,云南昆明650500 [2]保山中医药高等专科学校,云南保山678000

出　　处：《中国医药导报》2023年第6期59-62,共4页China Medical Herald

基　　金：云南省教育厅科学研究基金项目(2020J0142)。

摘　　要：糖脂代谢共同作用维持生命所需的能量,且糖代谢和脂代谢两者联系密切,相互影响,糖脂代谢紊乱是多种慢性病发生、发展的主要原因之一。芒果苷,又称莞知母宁,主要存在于常见芒果属及龙胆科植物。芒果苷具有各种药理学作用,在糖脂代谢性疾病中发挥不可或缺的作用。本文就近几年芒果苷的天然生物活性,主要分析并讨论芒果苷调节糖脂代谢的作用机制及生物利用度,为临床疾病预防应用、开发功能性药食品、生产优化等方面提供新思路。Glycolipid metabolism work together to maintain the energy needed for life,moreover,glucose metabolism and lipid metabolism are closely related and interact with each other.The disorder of glycolipid metabolism is one of the main reasons for the occurrence and development of various chronic diseases.Mangiferin,also known as formononetin,is mainly found in common plants of mangifera and gentianaceae.Mangiferin has various pharmacological effects and plays an indispensable role in glycolipid metabolic diseases.Based on the natural biological activity of mangiferin in recent years,this paper mainly analyzes and discusses the mechanism and bioavailability of mangiferin regulating glycolipid metabolism,in order to provide new ideas for clinical disease prevention and application,development of functional drug and food,and production optimization.

关 键 词：芒果苷 糖脂代谢 药理作用 生物利用度 

分 类 号：R589[医药卫生—内分泌]