Hyperthyroidism and severe bradycardia:Report of three cases and review of the literature  

作　　者：Yang-Li He Wen-Xing Xu Tuan-Yu Fang Min Zeng 

机构地区：[1]Center of Geriatrics,Hainan General Hospital,Haikou 570311,Hainan Province,China [2]Hainan Clinical Research Center for Cardiovascular Disease,Hainan General Hospital,Haikou 570311,Hainan Province,China [3]Center of Geriatrics,Hainan Affiliated Hospital of Hainan Medical University,Haikou 570311,Hainan Province,China [4]Department of Endocrine,Hainan General Hospital,Haikou 570311,Hainan Province,China

出　　处：《World Journal of Clinical Cases》2023年第7期1549-1559,共11页世界临床病例杂志

基　　金：the Clinical Medical Research Center Project of Hainan Province,China,No.LCYX202207;Key R&D Plan Project of Hainan Province,China,No.ZDYF2020118.

摘　　要：BACKGROUND Hyperthyroidism often leads to tachycardia,but there are also sporadic reports of hyperthyroidism with severe bradycardia,such as sick sinus syndrome(SSS)and atrioventricular block.These disorders are a challenge for clinicians.CASE SUMMARY We describe three cases of hyperthyroidism with SSS and found 31 similar cases in a PubMed literature search.Through the analysis of these 34 cases,we found 21 cases of atrioventricular block and 13 cases of SSS,with 67.6%of the patients experiencing bradycardia symptoms.After drug treatment,temporary pacemaker implantation,or anti-hyperthyroidism treatment,the bradycardia of 27 patients(79.4%)was relieved,and the median recovery time was 5.5(2-8)d.Only 7 cases(20.6%)needed permanent pacemaker implantation.CONCLUSION Patients with hyperthyroidism should be aware of the risk of severe bradycardia.In most cases,drug treatment or temporary pacemaker placement is recommended for initial treatment.If the bradycardia does not improve after 1 wk,a permanent pacemaker should be implanted.

关 键 词：HYPERTHYROIDISM BRADYCARDIA Sick sinus syndrome Atrioventricular block PACEMAKER Case report 

分 类 号：R581.1[医药卫生—内分泌] R541.72[医药卫生—内科学]