Ochronotic arthropathy of bilateral hip joints:A case report  

作　　者：Nicolas Yap San Min Urba Rafi Juan Wang Bin He Lei Fan 

机构地区：[1]Department of Orthopedics,The Second Affiliated Hospital of Nanjing Medical University,Nanjing 210011,Jiangsu Province,China [2]Department of Ultrasonography,The Second Affiliated Hospital of Nanjing Medical University,Nanjing 210011,Jiangsu Province,China

出　　处：《World Journal of Clinical Cases》2023年第1期210-217,共8页世界临床病例杂志

摘　　要：BACKGROUND Ochronosis,also known as alkaptonuria,is a rare autosomal recessive selfmetabolic disease arising from deficiency of homogentisate 1,2 dioxygenase enzyme.It affects several organs and muscoskeletal structures.We herein report a case of a patient who presented with severe hip arthropathy complicated with late stage ochronosis.CASE SUMMARY A 56-year-old male patient was admitted in our department in 2019 with complaints of chronic low backache and left hip pain.After the required investigations were done,lumbar disc herniation and severe hip arthritis were the initial diagnosis.A total left hip arthroplasty was performed.Ochronotic osteoarthritis was only obtained post-surgery as confirmatory diagnosis.He was again admitted mid 2022 with the same complaints on the right hip.Subsequently,he underwent a total right hip arthroplasty.Post-operative recovery and follow-ups were deemed very satisfactory.CONCLUSION Ochronosis is an unusual diagnosis for a patient who presents with typical hip arthritis.Thus,unless meticulous history taking and advanced laboratory tests,the diagnosis can easily be missed by surgeons.

关 键 词：ALKAPTONURIA Metabolic disease Ochronotic osteoarthropathy Hip arthritis Bilateral hip arthroplasty Case report 

分 类 号：R68[医药卫生—骨科学]