抗疫生物材料  

Anti-epidemic Biological Materials

作　　者：杨勇[1,2] YANG Yong(State Key Laboratory of High-Performance Ceramics and Ultrastructure,Shanghai Institute of Ceramics,Chinese Academy of Sciences,Shanghai 200050,China;College of Materials Science and Opto-Electronic Technology,University of Chinese Academy of Sciences,Beijing 100049,China)

机构地区：[1]中国科学院上海硅酸盐研究所,高性能陶瓷与超微结构国家重点实验室,上海200050 [2]中国科学院大学材料科学与光电技术学院,北京100049

出　　处：《无机材料学报》2023年第1期1-2,共2页Journal of Inorganic Materials

摘　　要：致病性细菌和病毒以及癌细胞在人体内可快速甚至爆炸性增殖,长期对人类生命健康造成严重威胁。特别是2019年末,全球范围内暴发的新冠病毒肺炎疫情引起了全球对此类重大突发公共卫生事件的高度关注。细菌、病毒、癌细胞的快速检测、诊断及治疗对维护人类生命健康发挥着重要作用。除了常规的医学诊疗手段,基于一些功能纳米材料发展的新型传感技术,对病毒、细菌、癌细胞的检测及对三者引起的疾病治疗,展现出广阔的发展前景,但在新型诊疗策略向临床验证转化方面还面临着生物活性、稳定性、可重复性等挑战。目前实际用于临床诊疗的新技术非常少。Pathogenic bacteria and viruses and cancers pose serious long-term threats to human life and health because of their quick or even explosive proliferation in the body.In particular,the global outbreak of COVID-19 in late 2019 has raised high concerns about this major public health emergency.Rapid detection,diagnosis and treatment of bacteria,viruses and cancer cells play an important role in maintaining human life and health.In addition to conventional medical diagnostic and therapeutic means,novel sensing technologies based on certain functional materials have shown promising development prospects for the detection and treatment of viruses,bacteria and cancer cells.However,the transition from novel diagnosis and treatment strategies to clinical validation still faces challenges such as biological activity,stability and reproducibility.Currently,few new technologies are actually used in clinical diagnosis and treatment.A number of functional materials,with excellent electrical,magnetic,optical and other properties,can be applied to construct biosensors with fast response,high sensitivity and high accuracy.Particularly,nanoscale materials exhibit excellent sensing properties due to their peculiar surface properties,quantum size effects and small-size effects,which can be used for therapeutic purposes through photothermal,magnetothermal and high catalytic activity with promising integration of diagnosis and treatment.With the development of nanomaterials,nano-sensing technology and biotechnology,combination of materials and medical detection are not only committed to controlling the existing large-scale outbreaks and realizing the rapid screening and diagnosis of biomolecules,but also hoped to build a universal detection and diagnosis platform to timely respond to various outbreaks and diseases.In the field of biological materials and medical detection,on the one hand,we need to consider whether the properties of a material can be affected by factors in the biological environment,such as misjudgment of results caus

关 键 词：医学诊疗 诊疗策略 临床验证 重大突发公共卫生事件 癌细胞 临床诊疗 功能纳米材料 可重复性 

分 类 号：R318.08[医药卫生—生物医学工程]