2020-2021年南宁市新报告HIV感染者合并HCV和梅毒情况及相关因素  

HCV and TP co-infection among patients with human immunodeficiency virus in Nanning from 2020 to 2021

作　　者：潘海西[1] 黄秋芳[1] 成肖阳 秦剑秋[1] PAN Haixi;HUANG Qiufang;CHENG Xiaoyang;QIN Jianqiu(Nanning Municipal Center for Disease Control and Prevention,Nanning 530023,China)

机构地区：[1]南宁市疾病预防控制中心,南宁530023

出　　处：《中国艾滋病性病》2023年第1期102-105,共4页Chinese Journal of Aids & STD

基　　金：广西壮族自治区卫生健康委员会自筹基金项目(Z20200899,Z-A20221265);南宁市科学研究与技术开发计划项目(20223051)。

摘　　要：目的分析南宁市HIV感染者中HCV及梅毒感染的流行情况,为南宁市艾滋病的综合防治提供科学依据。方法对2020年1月至2021年12月在南宁市疾病预防控制中心首次发现的HIV感染者进行HCV抗体和梅毒血清特异性抗体及非特异性抗体检测,收集性别、年龄、婚姻、民族、文化程度等人口学特征及行为学特征,采用二分类Logistic回归进行单因素和多因素分析。结果共有1858例HIV感染者列入分析,其中男性1369例(73.68%),平均年龄52.71岁,已婚者1000例(53.82%),初中及以下文化程度1464例(78.79%),以异性性传播为主,占89.56%(1664例)。HIV-HCV、HIV-TP和HIV-HCV-TP共感染分别为39例(2.10%)、136例(7.32%)和2例(0.11%)。多因素Logistic回归分析显示,同性性传播(OR=8.767,95%CI:1.671~45.997)及静脉吸毒(OR=276.060,95%CI:97.574~781.039)是合并HCV感染的危险因素,同性性传播(OR=2.347,95%CI:1.250~4.405)是梅毒感染的危险因素。结论南宁市新报告HIV感染者中梅毒感染率较高,在进行HIV检测时建议进行梅毒筛查,降低梅毒感染对HIV传播促进作用。虽然合并HCV的感染率不高,但是此人群依旧存在,仍然需要对同性性传播和吸毒人群等重点人群关注。Objective To understand HCV and TP co-infection among patients with human immunodeficiency virus in Nanning to provide references for the effective prevention and treatment of HIV patients.Methods Data of HIVinfected persons who were first confirmed in Nanning Center for Disease Control and Prevention were collected and analyzed from January 2020 to December 2021,including information on sex,age,marriage,nationality,education level,route of transmission,etc.The result of serological tests for anti-HCV and anti-TP and univariate and multivariate analysis was performed using the binary Logistic regression model.Results A total of 1858 patients with HIV infection were in this study,including 1369(73.68%)males,with an average age of 52.71 years old(16~90).1000(53.82%)were married,1464(78.79%)with education of junior high school or below and 1664(89.56%)were transmitted through heterosexual contact.The co-infection rates of HIV-HCV,HIV-TP,and HIV-HCV-TP were 39(2.10%),136(7.32%),and 2(0.11%),respectively.Multivariate Logistic regression analysis showed that homosexual transmission(OR=8.767,95%CI:1.671-45.997)and intravenous drug users(OR=276.060,95%CI:97.574-781.039)were the risk factors of HCV infection.Homosexual transmission(OR=2.347,95%CI:1.250-4.405)was the risk factor of TP infection.Conclusions The prevalence of HIV/TP co-infected patients is high,suggesting that the patients should be carried out simultaneously with HIV testing and TP testing to reduce HIV transmission.Since some HIV/HCV co-infected patients are noticed,which reminds us that this population is one of the targets.

关 键 词：艾滋病病毒 丙型肝炎病毒 梅毒 合并感染 

分 类 号：R512.91[医药卫生—内科学] R512.6[医药卫生—临床医学]