铺棉灸联合刺络拔罐治疗带状疱疹后遗神经痛临床研究  

Clinical study on cotton-covered moxibustion combined with blood-pricking and cupping therapy on postherpetic neuralgia

作　　者：朱梅[1] 张玉珍[1] 刘影 ZHU Mei;ZHANG Yuzhen;LIU Ying(Department of Dermatology,Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610072,China)

机构地区：[1]成都中医药大学附属医院皮肤科,四川成都610072

出　　处：《陕西中医》2023年第3期375-378,共4页Shaanxi Journal of Traditional Chinese Medicine

基　　金：四川省中医药科学技术研究专项课题(2016Q020)。

摘　　要：目的:观察铺棉灸联合刺络拔罐治疗带状疱疹后遗神经痛(PHN)的临床疗效。方法:将126例PHN患者随机分为观察组和对照组,各63例。对照组采用刺络拔罐治疗,观察组在对照组的基础上联合铺棉灸进行治疗。比较两组患者临床疗效、中医临床症状评分、生化指标、视觉模拟评分法(VAS)、匹兹堡睡眠质量指数(PSQI)和不良反应发生情况。结果:观察组治疗总有效率为92.06%,高于对照组的76.19%,差异有统计学意义(P<0.05)。治疗后,两组患者中医症状评分均降低,且观察组低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组患者β-内啡肽高于对照组,差异有统计学意义(均P<0.05)。治疗后,观察组血清P物质及降钙素基因相关肽低于对照组,差异有统计学意义(均P<0.05)。治疗后,两组患者VAS、PSQI评分均降低,且观察组低于对照组,差异有统计学意义(均P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论:铺棉灸联合刺络拔罐治疗PHN临床疗效较好,患者中医症状积分、疼痛及睡眠状况等均得到改善,且不良反应较少。Objective:To observe the clinical efficacy of cotton-covered moxibustion combined with blood-pricking and cupping therapy on patients with postherpetic neuralgia(PHN).Methods:126 patients with PHN were randomly classified into observation group(63 cases)and control group(63 cases)randomly.The control group adopted blood-pricking and cupping therapy,and the observation group combined with cotton-covered moxibustion on the basis of the control group.Clinical efficacy,scores of clinical TCM symptoms,biochemical indicators,visual analogue scale score(VAS),Pittsburgh sleep quality index(PSQI)and occurrence of adverse reactions were compared between the two groups.Results:The total effective rate of treatment was 92.06%in the observation group,which was higher than 76.19%in the control group,difference statistically significant(P<0.05).After treatment,the scores of TCM symptoms of the two groups were reduced,and the scores in the observation group were lower than those in the control group,difference statistically significant(P<0.05).After treatment,compared to the control group the level ofβ-endorphin in the observation group was higher,while the levels of serum substance P and calcitonin gene-related peptide lower,difference statistically significant(all P<0.05).After treatment,the scores of VAS and PSQI were decreased in the two groups,and the scores in the observation group were lower compared with those in the control group,difference statistically significant(all P<0.05).There were no significant differences in the incidence rates of adverse reactions between the two groups(P>0.05).Conclusion:Cotton-covered moxibustion combined with blood-pricking and cupping therapy has significant clinical efficacy on PHN.It can significantly improve the clinical TCM symptoms,pain and sleep status of patients,and does not cause obvious adverse reactions.

关 键 词：带状疱疹后遗神经痛 铺棉灸 刺络拔罐 疼痛因子 睡眠质量 不良反应 

分 类 号：R752.1[医药卫生—皮肤病学与性病学]