静电纺丝牙周再生材料构建策略和发展趋势  

A review of electrospinning materials in periodontal regeneration:fabrication strategies and development trends

作　　者：李茂雪 程国平 郭淑娟[1] 丁一[1] Maoxue Li;Guoping Cheng;Shujuan Guo;Yi Ding(State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases&Department of Periodontics,West China Hospital of Stomatology,Sichuan University,Chengdu,Sichuan Province,P.R.China)

机构地区：[1]四川大学华西口腔医院牙周病科,口腔疾病研究国家重点实验室,国家口腔疾病临床医学研究中心

出　　处：《中国口腔医学继续教育杂志》2023年第1期12-17,共6页Chinese Journal of Stomatologial Continuing Education

基　　金：国家自然科学基金(项目编号:82071121)。

摘　　要：静电纺丝纳米纤维材料可以模拟天然的细胞外基质结构,具有比表面积大、孔隙率高等优点,有利于细胞的长入,并可作为载体搭载生物活性物质,满足牙周组织再生要求。利用静电纺丝技术研发牙周再生生物材料是当前牙周组织工程的热点,本文综述了近年来基于静电纺丝技术研发牙周组织再生生物材料体系组成和构建策略,并对未来的研发趋势进行讨论和展望。Electrospinning nanofiber materials can mimic the natural extracellular matrix structure with their high specific surface area and porosity,and can serve as carriers for bioactive substances that may be required to regenerate periodontal tissues and promote cell growth.Electrospinning nanofiber materials is a current hotspot in periodontal tissue engineering.In this paper,we discuss future development trends as well as the compositions and fabrication strategies of periodontal tissue regenerative biomaterials systems based on electrospinning technology.

关 键 词：牙周炎 牙周组织再生 静电纺丝 牙周复合体 

分 类 号：TQ3[化学工程]