一例溴敌隆中毒凝血功能障碍合并血栓的病例分析  

A case of analysis of coagulation dysfunction complicated with thrombus caused by bromadiolone poisoning

作　　者：任英 马欣 顾平[3] REN Ying;MA Xin;GU Ping(Dept.of Pharmacy,People’s Hospital of Shache,Kashi 844700,China;不详)

机构地区：[1]莎车县人民医院药剂科,新疆喀什844700 [2]大英县人民医院药剂科,四川遂宁629300 [3]遂宁市中心医院药剂科,四川遂宁629000

出　　处：《中国处方药》2023年第2期72-74,共3页Journal of China Prescription Drug

摘　　要：目的 探讨1例溴敌隆中毒凝血功能障碍合并血栓的病例,制定最合适患者的抗凝治疗方案。方法 临床药师通过查阅指南、共识及文献,制定溴敌隆中毒凝血功能障碍合并血栓患者的止血与抗凝治疗方案。结果 溴敌隆中毒凝血功能障碍合并血栓患者,可以通过使用止血药维生素K1纠正凝血功能,并使用抗凝药物低分子肝素序贯利伐沙班治疗下肢静脉血栓。结论 溴敌隆中毒并发血栓形成后的治疗仍以抗凝为主,但何种抗凝药物更有优势,有待进一步研究。Objective To discuss a case of blood coagulation dysfunction complicated with thrombosis caused by bromadiolone poisoning to formulate the best treatment for patients.Methods The clinical pharmacist formulates the hemostasis and anticoagulation treatment plan for patients with bromadiolone poisoning and coagulation dysfunction combined with thrombosis by consulting the guidelines, consensus and literature.Results Patients with coagulation dysfunction complicated with thrombosis caused by bromadiolone poisoning can correct the coagulation function by using the hemostatic drug vitamin K1, and use the anticoagulant drug low molecular weight heparin sequential rivaroxaban to treat lower extremity venous thrombosis.Conclusion Anticoagulation is still the main treatment for bromadiolone poisoning complicated with thrombosis, but which anticoagulant drug has more advantages needs to be further studied.

关 键 词：溴敌隆 凝血功能障碍 止血药 抗凝药物 

分 类 号：R595.4[医药卫生—内科学]