盐酸达克罗宁胶浆联合利多卡因在表面麻醉下经尿道输尿管镜置入输尿管导管中的应用效果  

Observation on the application of Dacronin Hydrochloride Mucilage combined with Lidocaine in transurethral ureteroscopy under surface anesthesia

作　　者：赖慧 钟清华 叶红娣 LAI Hui;ZHONG Qinghua;YE Hongdi(Operating Room,Ganzhou Tumor Hospital,Jiangxi Province,Ganzhou 341000,China)

机构地区：[1]江西省赣州市肿瘤医院手术室,江西赣州341000

出　　处：《中国当代医药》2023年第6期100-103,共4页China Modern Medicine

基　　金：江西省赣州市指导性科技计划项目(GZ2021ZSF 335)。

摘　　要：目的探讨盐酸达克罗宁胶浆联合利多卡因在表面麻醉下经尿道输尿管镜置入输尿管导管中的应用效果。方法选取2021年9月至2022年5月在赣州市肿瘤医院接受表面麻醉下经尿道输尿管镜置入输尿管导管的共计80例患者作为研究对象,按照随机数字表法分成研究组(40例)与对照组(40例),对照组给予利多卡因麻醉,研究组在对照组基础上联合盐酸达克罗宁胶浆麻醉,比较两组患者躁动情况、疼痛程度、生命体征及应激反应。结果研究组患者的躁动发生率低于对照组,差异有统计学意义(P<0.05);研究组患者的疼痛发生率低于对照组,差异有统计学意义(P<0.05);整体分析发现:心率(HR)、平均动脉压(MAP)组间比较、时间点比较及交互作用比较,差异均有统计学意义(P<0.05),进一步两两比较,两组患者术后3、6 h的HR快于术前、MAP高于术前,两组患者术后6 h的HR慢于本组术前3 h、MAP低于本组术前3 h,差异有统计学意义(P<0.05)。研究组患者术后3、6 h的HR慢于对照组同期、MAP低于对照组同期,差异有统计学意义(P<0.05);肾上腺素(E)、去甲肾上腺素(NE)组间比较、时间点比较及交互作用比较,差异均有统计学意义(P<0.05),进一步两两比较,两组患者术后3、6 h的E、NE高于本组术前,两组患者术后6 h的E、NE低于本组术前3 h,差异有统计学意义(P<0.05)。研究组患者术后3、6 h的E、NE低于对照组同期,差异有统计学意义(P<0.05)。结论在表面麻醉下经尿道输尿管镜置入输尿管导管中给予盐酸达克罗宁胶浆联合利多卡因,能够改善患者躁动情况,降低疼痛程度,减少生命体征波动和机体应激反应。Objective To investigate the application effect of Dyclonine Hydrochloride Mucilage combined with Lidocaine in transurethral ureteroscope placement of ureteral catheter under topical anesthesia.Methods From September 2021 to May 2022,a total of 80 patients who were underwent transurethral ureteroscopy with ureteral catheter placement in Ganzhou Tumor Hospital under topical anesthesia were selected as the research subjects,and divided into the study groups(40 cases)the control group(40 cases)according to the random number table method.The control group was given Lidocaine anesthesia,and the study group was combined with Dyclonine Hydrochloride Mucilage anesthesia on the basis of the control group.The restlessness,pain degree,vital signs and stress response of the two groups were compared.Results The incidence of agitation in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).The incidence of pain in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).The overall analysis showed that heart rate(HR),mean arterial pressure(MAP)between groups,time point comparison and interaction differences were statistically significant(P<0.05).HR at 3 and 6 hours after operation was faster than that before operation,and MAP was higher than before operation,HR at 6 hours after operation in the two groups was slower than that at 3 hours before operation,and MAP was lower than that at 3 hours before operation,and the differences were statistically significant(P<0.05).HR in the study group at 3 and 6 hours after operation was slower than that in the control group at the same period,and MAP was lower than that in the control group at the same period,the differences were statistically significant(P<0.05).Epinephrine(E),norepinephrine(NE)between groups,time point comparison and interaction differences were statistically significant(P<0.05).Further pairwise comparison,E and NE of the two groups at 3 and 6 h after sur

关 键 词：表面麻醉 输尿管镜 输尿管导管 盐酸达克罗宁胶浆 利多卡因 

分 类 号：R614[医药卫生—麻醉学]