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作 者:庞世刚[1] 韩红波[1] Pang Shi-gang;Han Hong-bo(Binzhou Central Hospital,Binzhou 251799,Shandong Province,China)
出 处:《中外医药研究》2022年第13期12-14,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
摘 要:目的:比较腹腔镜阑尾切除术与开腹阑尾切除术的临床效果。方法:选取2021年5月-2022年5月滨州市中心医院收治的阑尾炎患者40例为观察对象,根据手术方案不同将患者分为对照组和观察组,各20例。对照组实施常规开腹阑尾切除术治疗,观察组实施腹腔镜阑尾切除术治疗。比较两组患者各项手术指标、血清细胞因子水平[胃动素(MTL)、二胺氧化酶(DAO)、反应蛋白(CRP)、降钙素原(PCT)]、疼痛程度[数字评分法(NRS)]。结果:观察组手术时间、肛门排气时间及住院时间均短于对照组,出血量少于对照组,差异有统计学意义(P<0.05);术后,两组患者MTL水平均降低,DAO、CRP、PCT水平均升高,观察组MTL水平高于对照组,DAO、CRP、PCT水平低于对照组,差异有统计学意义(P<0.05);术后即刻、术后30 min、术后24 h,两组患者NRS评分均降低,观察组NRS评分低于对照组,差异有统计学意义(P<0.05)。结论:在对阑尾炎患者实施腹腔镜阑尾切除术,可缩短患者手术时间、肛门排气时间、住院时间,减少出血量,减轻患者疼痛程度,改善患者血清细胞因子水平。Objective:To compare the clinical effects of laparoscopic appendectomy and open appendectomy.Methods:Forty patients with appendicitis admitted to Binzhou Central Hospital from May 2021 to May 2022 were selected as the observation objects.According to different surgical programs,the patients were divided into control group and observation group,with 20 cases in each group.The control group received conventional open appendectomy,and the observation group received laparoscopic appendectomy.Surgical indicators,serum cytokine levels[motilin(MTL),diamine oxidase(DAO),reactive protein(CRP),procalcitonin(PCT)]and pain degree[digital scoring method(NRS)]were compared between the two groups.Results:The operation time,anal exhaust time and hospital stay in the observation group were shorter than those in the control group,and the blood loss was less than that in the control group,the difference was statistically significant(P<0.05).After surgery,MTL levels were decreased in both groups,while DAO,CRP and PCT levels were increased.MTL levels in the observation group were higher than those in the control group,while DAO,CRP and PCT levels were lower than those in the control group,with statistical significance(P<0.05).Immediately after surgery,30 min after surgery and 24 h after surgery,NRS score of 2 groups was decreased,and NRS score of observation group was lower than control group,the difference was statistically significant(P<0.05).Conclusion:Laparoscopic appendectomy in patients with appendicitis can shorten the operation time,anal exhaust time,hospital stay,reduce the amount of blood loss,reduce the degree of pain,and improve the serum cytokine level of patients.
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