煤工尘肺中医证候与理化检查指标的关系  

Correlation between TCM syndromes and physical and chemical examination indices of coal workers with pneumoconiosis

作　　者：白晓旭[1] 李秀兰 牛少强[2] 王勇奇 张红[4] BAI Xiaoxu;LI Xiulan;NIU Shaoqiang;WANG Yongqi;ZHANG Hong(Department of Science and Education,Fangshan Hospital of Beijing University of Chinese Medicine,Beijing 102400,China;DepartmentⅢof Pulmonary Diseases,Fangshan Hospital of Beijing University of Chinese Medicine,Beijing 102400,China;DepartmentⅡof Pulmonary Diseases,Fangshan Hospital of Beijing University of Chinese Medicine,Beijing 102400,China;Department of TCM Internal Medicine,Fangshan Hospital of Beijing University of Chinese Medicine,Beijing 102400,China)

机构地区：[1]北京中医药大学房山医院科教科,北京102400 [2]北京中医药大学房山医院肺病3科,北京102400 [3]北京中医药大学房山医院肺病2科,北京102400 [4]北京中医药大学房山医院中医内科,北京102400

出　　处：《中国医药科学》2023年第4期4-7,共4页China Medicine And Pharmacy

基　　金：“首都临床特色应用研究”专项课题(Z161100000516121);北京市中医药科技发展资金项目(JJ-2020-44)。

摘　　要：目的探讨煤工尘肺中医证候与理化检查指标的关系。方法2017年1月至2020年12月,收集在北京中医药大学房山医院就诊的208例煤工尘肺患者中医四诊信息以及血常规、血气检查结果。统计分析中医证候与血常规、血气分析的关系。结果出现频率>1%的中医证候有15个,以肺气虚证为主。中医证候在血小板计数(PLT)、氧分压(PaO_(2))比较,差异有统计学意义(P<0.05)。PLT是风寒犯肺证的独立危险因素,PLT越高,风寒犯肺证可能性越小(P<0.05,OR<1)。PaO_(2)是血瘀证、痰湿阻肺证独立危险因素,PaO_(2)越高,血瘀证可能性越大(P<0.05,OR>1),痰湿阻肺的可能性越小(P<0.05,OR<1)。结论煤工尘肺患者中医证候以肺气虚证为主,PLT、PaO_(2)可作为中医证候分型参考标准。Objective To investigate the correlation between TCM syndromes and physical and chemical examination indices of coal workers with pneumoconiosis.Methods A total of 208 cases of coal workers with pneumoconiosis admitted to and treated in Fangshan Hospital of Beijing University of Chinese Medicine from January 2017 to December 2020 were collected,including the information of four conventional Chinese medicine diagnoses,and blood routine and blood gas examination results.The correlation between TCM syndromes,blood routine and blood gas analysis were counted and analyzed.Results There were 15 TCM syndromes with frequency>1%,mainly pulmonary qi deficiency syndrome.There were statistically significant differences in platelet count(PLT)and oxygen partial pressure(PaO_(2))between TCM syndromes(P<0.05).PLT was an independent risk factor of wind-cold invading pulmonary syndrome.The higher the PLT was,the less likely the wind-cold invading pulmonary syndrome was to occur(P<0.05,OR<1).PaO_(2)was an independent risk factor of blood stasis syndrome and phlegm-dampness obstructing pulmonary syndrome.The higher the PaO_(2)was,the greater the possibility of blood stasis syndrome was(P<0.05,OR>1),and the lower the possibility of phlegm-dampness obstructing pulmonary syndrome was(P<0.05,OR<1).Conclusion The TCM syndromes of coal workers with pneumoconiosis are mainly pulmonary qi deficiency syndrome,and PLT and PaO_(2)can be used as reference standards for TCM syndrome classification.

关 键 词：煤工尘肺 中医证候 血常规 血气分析 

分 类 号：R259[医药卫生—中西医结合]