中药血清药物化学研究现状  

Status quo of research on the serum pharmaceutical chemistry of Chinese materia medica

作　　者：陈旺宇 节笑笑 陈甜甜 张月 郝旭亮 CHEN Wangyu;JIE Xiaoxiao;CHEN Tiantian;ZHANG Yue;HAO Xuliang(Institute of Chinese Materia Medica Prescriptions,Shanxi Academy of Traditional Chinese Medical,Shanxi,Taiyuan 030000,China;Graduate School of Shanxi University of Chinese Medicine,Shanxi,Jinzhong 030619,China;The Hospital of Shanxi University of Chinese Medicine,Shanxi,Taiyuan 030000,China)

机构地区：[1]山西省中医药研究院中药方剂研究所,山西太原030000 [2]山西中医药大学研究生院,山西晋中030619 [3]山西中医药大学附属医院,山西太原030000

出　　处：《中国医药科学》2023年第4期26-29,86,共5页China Medicine And Pharmacy

基　　金：山西省中医药研究院中药新药研究专项(2016XYZX02);山西省卫生健康委员会重点实验室建设计划(2020SYS09)。

摘　　要：中药血清药物化学是一种分析口服药物后血中移行成分的方法。近年来,中药血清药物化学得到大量学者认可并被广泛应用。本文梳理近年来国内外相关文献,对中药血清药物化学研究中选择实验动物、设计给药方案、采集血清、制备血清样品等关键技术进行归纳总结,并对中药血清药物化学具体应用和方法拓展进行多方面综述。在此基础上,分析中药血清药物化学可能存在的问题,展望其应用前景,以期为中药血清药物化学在研究领域中深入应用提供参考。Serum pharmaceutical chemistry of Chinese materia medica is a method to analyze the migration components in blood after oral administration of drugs.In recent years,serum pharmaceutical chemistry of Chinese materia medica has been recognized by a large number of scholars and widely used.In this paper,the related literatures at home and abroad in recent years are sorted out,and the key technologies in the research of serum pharmaceutical chemistry of Chinese materia medica,such as selecting experimental animals,designing administration scheme,collecting serum,and preparing serum samples,are induced and summarized.Meanwhile,the specific application and method expansion of serum pharmaceutical chemistry of Chinese materia medica are reviewed in many aspects.On this basis,the possible problems of serum pharmaceutical chemistry of Chinese materia medica are analyzed.And its application prospect is explored,so as to provide reference for further application of serum pharmaceutical chemistry of Chinese materi a medica in the research field.

关 键 词：血清药物化学 血中移行成分 中药 药效物质基础 

分 类 号：R285.5[医药卫生—中药学]