腹膜后Castleman病1例报告并文献复习  

A case report of retroperitoneal Castleman disease and literature review

作　　者：江书典 江敏芝 胡明政[1] JIANG Shudian;JIANG Minzhi;HU Mingzheng(Department of Hepatobiliary and Pancreatic Surgery,the First Clinical Medical College of China Three Gorges University,Yichang Central People’s Hospital,Hubei,Yichang 443003,China)

机构地区：[1]三峡大学第一临床医学院,湖北省宜昌市中心人民医院肝胆胰外科,湖北宜昌443003

出　　处：《中国医药科学》2023年第4期185-188,192,共5页China Medicine And Pharmacy

摘　　要：腹膜后Castleman病(CD)是一种临床上较为罕见的病种,各个年龄阶段均可发病,男女发病率无明显差异,临床表现及影像学特征表现均不典型,临床上将其分为单中心型及多中心型,单中心型最好发于纵隔,以腹膜后最为少见,手术完整切除病灶是该病主要的治疗方案,其预后良好,远期生存率高,多中心型目前尚无统一的治疗方案,预后较差,病死率较高。临床上此病不易被诊断,故其漏诊及误诊率相对较高。本文整合1例腹膜后CD患者的临床病例,通过报道该病的相关临床知识,并结合既往文献,予以总结该病的病因、发病机制、临床特征、病理、诊断、治疗及预后。从而增加广大临床学者对该病的了解。Retroperitoneal Castleman disease is a relatively rare disease in clinic,which can occur at all ages.There is no significant difference in morbidity between men and women,and the clinical manifestations and imaging features are atypical.Clinically,the disease can be divided into the monocentric type and the polycentric type.The monocentric type is most likely to occur in the mediastinum,and the retroperitoneal type is the least likely to occur.Complete surgical resection of the lesion is the main treatment scheme for the disease,which has a good prognosis and a high long-term survival rate.There is no unified treatment scheme for the polycentric type now.Meanwhile,the prognosis is poor,and the mortality rate is relatively high.Clinically,this disease is difficult to be diagnosed,so the rates of missed diagnosis and misdiagnosis are relatively high.A clinical case of retroperitoneal CD is integrated in this paper.By reporting the related clinical knowledge of the disease,and combining the previous literature,the etiology,pathogenesis,clinical features,pathology,diagnosis,treatment and prognosis of the disease are summarized,with an aim to increase the knowledge of the majori ty of clinical scholars on the disease.

关 键 词：腹膜后 CASTLEMAN病 临床特征 病理 治疗 

分 类 号：R551.2[医药卫生—血液循环系统疾病]