胺碘酮联合厄贝沙坦治疗心力衰竭合并频发室性早搏的临床效果观察  

Clinical effect of Amiodarone combined with Irbesartan in the treatment of heart failure complicated with frequent premature ventricular contractions

作　　者：马国镇 房佳蕊 MA Guozhen;FANG Jiarui(Department of Cardiovascular Medicine,The Third People’s Hospital of Huizhou City,Huizhou,Guangdong 516000,China;Second District,Department of Cardiovascular Medicine,The Third People’s Hospital of Huizhou City,Huizhou,Guangdong 516000,China)

机构地区：[1]惠州市第三人民医院心血管内科,广东惠州516000 [2]惠州市第三人民医院心血管内科二区,广东惠州516000

出　　处：《医药前沿》2022年第34期21-23,共3页Journal of Frontiers of Medicine

摘　　要：目的:观察胺碘酮与厄贝沙坦联合治疗心力衰竭合并频发室性早搏的临床效果。方法:选取2020年11月—2021年11月于惠州市第三人民医院接受治疗的46例心力衰竭合并频发性室性早搏患者,采用随机数字表法分为单一组与联合组各23例。单一组患者采用胺碘酮治疗,联合组患者采用胺碘酮联合厄贝沙坦治疗。对比两组心功能指标、6 min步行距离、治疗有效率、心功能分级。结果:治疗前,单一组与联合组患者心功能指标、6 min步行距离比较,差异无统计学意义(P>0.05)。治疗后,联合组患者心功能指标、6 min步行距离优于单一组,差异有统计学意义(P<0.05)。联合组治疗总有效率(95.65%)高于单一组(60.87%),差异有统计学意义(P<0.05);治疗前,单一组与联合组患者心功能分级比较,差异无统计学意义(P>0.05)。治疗后,联合组心功能分级优于单一组,差异有统计学意义(P<0.05)。结论:心力衰竭合并频发性室性早搏患者予以胺碘酮与厄贝沙坦联合治疗可加快患者心功能恢复,改善心功能分级,疗效确切,临床应用价值高。Objective To study and analyze the application of the combination of amiodarone and irbesartan in patients with heart failure and frequent premature beats.Methods A total of 46 patients with heart failure complicated with frequent premature ventricular beats who received treatment in the Third People’s Hospital of Huizhou City from November 2020 to November 2021 were selected and divided into a single group(23 cases)and a combined group(23 cases)by random number table method.Patients in the single group were treated with Amiodarone,and patients in the combined group were treated with Irbesartan on the basis of the above,The two groups were compared,including cardiac function indexes,6-minute walking distance,treatment response rate,and cardiac function grade.Results There was no significant difference between the single group and the combined group in terms of cardiac function index,6-minute walking distance and pre medication(P>0.05),but they improved after medication.The combined group had significant improvement effect(P<0.05);The total effective rate of the single group(60.87%)was lower than that of the combined group(95.65%),and there was a statistical difference between the groups(P<0.05);There was no significant difference in the cardiac function grading between the single group and the combined group before treatment(P>0.05).Compared with the single group,the combined group had better cardiac function grading after treatment(P<0.05).Conclusion Amiodarone combined with Irbesartan can accelerate the recovery of cardiac function and improve the classification of cardiac function in patients with heart failure and frequent ventricular premature beats.

关 键 词：频发性室性早搏 心力衰竭 厄贝沙坦 胺碘酮 心功能 

分 类 号：R541.6[医药卫生—心血管疾病]