基于大数据平台软件分析张家港地区变应原谱  

Analysis on the allergen spectrum in Zhangjiagang area based on big data platform and software

作　　者：杨慧珺 王天一 陆建斌 刘剑勇[1] 吴革平[1] 马行凯[1] YANG Huijun;WANG Tianyi;LU Jianbin;LIU Jianyong;WU Geping;MA Xingkai(Department of Otolaryngology,Zhangjiagang First People’s Hospital,Jiangsu,Suzhou 215600,China;Department of Internal Medicine,Zhangjiagang Dongcheng Community Health Service Center,Jiangsu,Suzhou 215600,China)

机构地区：[1]江苏省张家港市第一人民医院耳鼻咽喉科,江苏苏州215600 [2]江苏省张家港市东城社区卫生服务中心内科,江苏苏州215600

出　　处：《中国医药科学》2023年第3期166-170,共5页China Medicine And Pharmacy

基　　金：江苏省张家港市科技支撑计划(社会发展课题(ZKS1937))。

摘　　要：目的基于大数据平台分析张家港地区变应原谱特点,指导该区过敏性疾病防治工作的开展,为变应性鼻炎(AR)流行病学研究和诊治方案提供科学依据。方法应用张家港市第一人民医院耳鼻咽喉科自主研发的图文管理系统对2020年1月至2021年12月有AR临床症状的患者进行变应原皮肤点刺试验(SPT),将检测结果与患者性别、年龄、就诊月份等进行统计分析。结果4435例患者总阳性率为58.53%,12个月份间13种变应原均有分布,主要致敏原依次为粉尘螨、屋尘螨、蟑螂、链格孢、油菜花。阳性例数及阳性率最高的是青年组(18~44岁),除在少年组(7~17岁)中阳性率在性别上(男vs.女)差异有统计学意义(P<0.05)外,其余不同年龄组间男、女阳性率均差异无统计学意义(P>0.05)。比较变应原SPT阳性等级发现,粉尘螨、屋尘螨的SPT三级、四级阳性等级明显高,蟑螂、链格孢的SPT多为二、三级,其余变应原SPT多为一、二级。结论粉尘螨、屋尘螨是张家港地区AR的最主要致敏原,其SPT的阳性等级多为三、四级;其中阳性例数及阳性率最高的是青年组,少年组男性阳性率高于女性。Objective To analyze the characteristics of allergen spectrum in Zhangjiagang area based on big data platform,guide the conduct of allergic disease prevention and treatment work in this area,and provide scientific basis for the epidemiological research and diagnosis and treatment regimen of allergic rhinitis(AR).Methods The image and document management system independently developed by the Department of Otolaryngology of Zhangjiagang First People’s Hospital was utilized,and the allergen skin prick test(SPT)was performed on patients manifesting AR clinical symptoms from January 2020 to December 2021.The test results were statistically analyzed together with the patient’s sex,age,visit month,etc.Results The total positive rate in 4435 patients was 58.53%.Thirteen kinds of allergens were distributed among 12 months,and the main allergens were dust mites,house dust mites,cockroaches,Alternaria alternata and pollen in turn.The youth group(18-44 years old)had the highest number of positive cases and positive rate.Except that the positive rate in the juvenile group(7-17 years old)was significantly different between sexes(male vs.female)(P<0.05),there was no statistically significant difference in the positive rate between men and women in other age groups(P>0.05).By comparing the positive SPT grade of allergens,it was found that the positive SPT grades of dust mites and house dust mites were significantly higher,mainly grade 3 or 4.The positive SPT grades of cockroaches and Alternaria alternata were mostly grade 2 or 3,and the positive SPT grade of other allergens were mostly grade 1 or 2.Conclusion Dust mites and house dust mites are the main allergens leading to AR in Zhangjiagang area,and their positive SPT grades are mostly grade 3 or 4.The youth group has the highest number of positive cases and positive rate,and the positive rate in the male juvenile group is higher than that in the female juvenile group.

关 键 词：张家港地区 大数据平台 变应性鼻炎 变应原 致敏因素 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]