iVenomDB: A manually curated database for insect venom proteins  

作　　者：Longfei Chen Kun Lang Bo Zhang Jiamin Shi Xinhai Ye David W.Stanley Qi Fang Gongyin Ye 

机构地区：[1]State Key Laboratory of Rice Biology,Ministry of Agricultural and Rural Affairs Key Laboratory of Molecular Biology of Crop Pathogens and Insect Pests&Key Laboratory of Biology of Crop Pathogens and Insects of Zhejiang Province,Institute of Insect Sciences,College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China [2]College of Information Management,Nanjing Agricultural University,Nanjing,China [3]Biological Control of Insects Research Laboratory USDA/Agricultural Research Service,Columbia,MO,USA

出　　处：《Insect Science》2023年第1期264-266,共3页昆虫科学（英文版）

基　　金：supported by Major International(Regional)Joint Research Project of National Natural Science Foundation of China(Grant no.31620103915);the Program of National Natural Science Foundation of China(32072480);the Program for Chinese Innovation Team in Key Areas of Science and Technology of the Ministry of Science and Technology of the People's Republic of China(2016RA4008);the Fundamental Research Funds for the Central Universities(2021FZZX001-31)。

摘　　要：DearEditor,Venomous animals,such as snakes,insects(wasps,bees,ants,and some bugs),spiders,scorpions,and cone snails,use venom for predation and/or defense.Venom is mostly composed of proteinsand peptides.Because of their high potency and selectivity,venom components have been developed into valuable resources,such as research tools,bioinsecticides(Heep et al.,2019),and drug leads(Badawi,2021).The advent of high-throughput sequencing and mass spectrometry enabled exploration of venom components to new depths and at an unprecedented pace.To be useful to the scientific community,knowledge on these proteins must be stored in a retrievable manner,annotated,and curated.Currently,several databases are dedicated to venoms from a wide range of animals,such as Arachnoserver(Pineda et al.,2018),Conoserver(Kaas et al.,2012),and the Tox-Prot program within UniprotKB(Jungo et al.,2012).

关 键 词：mostly VENOM 

分 类 号：R99[医药卫生—毒理学]