Regio-and enantioselective conjugate addition ofβ-nitroα,β-unsaturated carbonyls to construct 3-alkenyl disubstituted oxindoles  

作　　者：Changli He Xiaoxue Tang Xin He Yuqiao Zhou Xiaohua Liu Xiaoming Feng 

机构地区：[1]Key Laboratory of Green Chemistry&Technology,Ministry of Education,College of Chemistry,Sichuan University,Chengdu 610064,China

出　　处：《Chinese Chemical Letters》2023年第1期337-341,共5页中国化学快报（英文版）

基　　金：financial support from the National Natural Science Foundation of China(No.21890723)。

摘　　要：Reversal of regioselectivity in the catalytic asymmetric conjugate additions of 3-substituted oxindoles toβ-nitroenones orβ-nitroacrylates was established with chiral scandium catalysts.It enabled the construction of functionalized 3,3-disubstituted oxindoles,including terminal and internal vinyl groups in excellent yields and ee values.

关 键 词：Asymmetric catalysis Conjugate addition NITROALKENES Regioselectivity OXINDOLES 

分 类 号：O621.251[理学—有机化学]