持久性有机污染物与妊娠期糖尿病关联研究进展  

Research progress on the relationship between persistent organic pollutants and gestational diabetes

作　　者：叶丽娅 朱舒奇 梁朝霞[1] Ye Liya;Zhu Shuqi;Liang Zhaoxia(Department of Obstetrics,Women′s Hospital,School of Medicine,Zhejiang University,Hangzhou 310006,China;Department of Obstetrics,Taizhou Hospital,Zhejiang University,Taizhou 317000,China)

机构地区：[1]浙江大学医学院附属妇产科医院产科,杭州310006 [2]浙江大学台州医院产科,台州317000

出　　处：《中华预防医学杂志》2023年第2期166-171,共6页Chinese Journal of Preventive Medicine

摘　　要：妊娠期糖尿病(gestational diabetes mellitus,GDM)是妊娠期常见的并发症之一,它与多种不良妊娠结局密切相关,严重危害母子健康,但其确切的发病机制目前尚不明确。近期研究发现长期接触持久性有机污染物(persistent organic pollutants,POPs)是妊娠期糖尿病发病风险因素之一,两者之间的关系已经受到越来越多的关注和重视。本文以国内外发表的文献为基础对POPs与GDM的相关性及其可能相关作用机制进行阐述,分析POPs与GDM之间的关联,从而为妊娠期糖尿病的预防提供新思路。Gestational diabetes mellitus(GDM)is one of the common complications during pregnancy.It is associated with many adverse pregnancy outcomes,threatening maternal and child health seriously.The exact pathogenesis of GDM remains unclear.Long term exposure to persistent organic pollutants(POPs)is considered to be one of the risk factors for GDM.More and more studies are concerned about the relationship between them.Based on the literature published at home and abroad,this article summarizes the correlation and possibly related mechanism of POPs and GDM,and explores the correlation between pops and GDM,so as to provide a new idea for the prevention of gestational diabetes.

关 键 词：妊娠期糖尿病 持久性有机污染物 代谢紊乱 胰岛素抵抗 

分 类 号：X592[环境科学与工程—环境工程] R714.256[医药卫生—妇产科学]