吸气峰流速仪在干粉吸入剂使用方法宣教中的应用  

Application of In-check DIAL G16 in dry powder inhaler

作　　者：蔡永桥 李静婷 强音[1] 李静 刘香男 杭晶卿[1] 王旋[1] CAI Yong-qiao;LI Jing-ting;QIANG Yin;LI Jing;LIU Xiang-nan;HANG Jing-qing;WANG Xuan(People’s Hospital of Putuo District,Shanghai 200060)

机构地区：[1]上海市普陀区人民医院,上海200060

出　　处：《中南药学》2023年第2期543-546,共4页Central South Pharmacy

摘　　要：目的 通过吸气峰流速仪判断患者吸气峰流速是否在最佳吸气范围,从而辅助患者调整吸气流速到最佳范围或更换治疗药物。方法 使用 In-check DIAL G16 吸气峰流速测试仪反复测试三次,以评估长期使用干粉吸入剂患者的吸气峰流速,并对吸气峰流速不佳的患者,使用吸气峰流速仪进行纠正,对纠正后仍不能达标的患者给予更换其他吸入给药装置。结果 首次评估有 25.00% 的患者吸气峰流速值不在最佳吸气流速范围,其中吸气峰流速> 90 L·min^(-1)的患者占 50.00%,30 ~ 60 L·min^(-1)的占 44.74%,< 30 L·min^(-1)的占 5.26%。第二次复诊时再次评估,不在最佳吸气流速范围内的患者占 11.11%,较第一次显著降低。第三次复诊时不在最佳吸气流速范围内的患者为 10.20%,与第二次相比差异无统计学意义。结论 吸气峰流速对于干粉吸入剂中药物在肺部的有效沉积至关重要,通过评估患者吸气峰流速值,使患者充分掌握“用力且深长”的吸气方法,可减少因吸气流速不达标而造成的临床疗效欠佳。Objective To determine whether the peak inspiratory flow rate falls in the appropriate range with In-check DIAL G16, and help patients to inhale at an optimal flow rate or change the therapeutic drug. Methods The In-check DIAL G16 device was used to assess the peak inspiratory flow rate for long-time users of dry powder inhalers. Meanwhile, patients who failed to inhale at the appropriate flow rate were corrected. For patients who still failed to meet the standard after the correction, the delivery device would be replaced. Results In the first evaluation, the peak inspiratory flow rate of 25% of patients failed to fall within the optimal inspiratory flow rate range, of which the inspiratory flow rate of 50% of the patients > 90 L·min^(-1), that of 44.74% of the patients ranged 30 ~ 60 L·min^(-1), and that of 5.26% patients < 30 L·min^(-1). After following up the patients,11.11% failed to fall within the optimal inspiratory flow rate range, much lower the second time. The third time, that number was 10.2% almost no difference between the second time and the third time.Conclusion Peak inspiratory flow rate is crucial for the dry powder to deposit effectively into the lungs. Patients may as well know the "forced and deep" inhaling method after evaluating the peak inspiratory flow rate, which would reduce the poor efficacy.

关 键 词：吸气峰流速 干粉吸入剂 支气管哮喘 慢性阻塞性肺疾病 药物治疗管理 

分 类 号：R969.3[医药卫生—药理学] R95[医药卫生—药学]