一种新型不对称菁类功能染料的合成与表征  

Synthesis and Characterization of a Novel Asymmetric Cyanine Functional Dye

作　　者：富莹莹 赵奎 魏崇斌 马明玉 洪建权 郑昌戈 Fu Yingying;Zhao Kui;Wei Chongbin;Ma Mingyu;Hong Jianquan;Zheng Changge(School of Chemistry and Materials Engineering,Jiangnan University,Wuxi Jiangsu 214122)

机构地区：[1]江南大学化学与材料工程学院,江苏无锡214122

出　　处：《山西化工》2023年第2期16-17,共2页Shanxi Chemical Industry

摘　　要：丙醛二乙基乙缩醛经Vilsmeier-Haack反应得到(E)-3-乙氧基-2-甲基丙烯醛(1);1与3-羧甲基绕丹宁反应得到了2-((E)-5-((E)-3-乙氧基-2-甲基亚烯基)-4-氧基-2-硫代噻唑烷-3-基)乙酸(2);2-甲基苯并唑与1,3-丙烷磺内酯反应得到2-甲基-3-(3-磺丙基)苯并[d]恶唑(3);2和3在碱性条件下反应得到了一种新型菁类染料(4)。通过1H NMR对化合物4的结构进行表征。对反应条件的优化确定NaOH的用量为2.2当量,反应温度为100℃,反应时间12 h,化合物4的最佳收率为78%。(E)-3-ethoxy-2-methylacrolein(1)was obtained from propionaldehyde diethylacetal via Vilsmeier-Haack reaction;1 reacted with 3-carboxymethyl rhodanine to obtain 2-((E)-5-((E)-3-ethoxy-2-methyleneyl)-4-oxo-2-thiothiazolidine-3-yl)acetic acid(2);2-methyl-3-(3-sulfopropyl)benzo[d]oxazole(3)was obtained by the reaction of 2-methylbenzozole with 1,3-propane sulfonolactone.A new cyanine dye was obtained by the reaction of 2 and 3 under alkaline conditions(4).The structure of compound 4 was characterized by1H NMR.The optimization of reaction conditions determined that the amount of Na OH was 2.2 equivalent,the reaction temperature was100℃,the reaction time was 12 hours,and the optimum yield of compound 4 was 78%.

关 键 词：不对称菁类染料 合成 苯并恶唑 硫代噻唑烷 

分 类 号：TQ572.31[化学工程—精细化工] TQ614.4