结缔组织疾病相关间质性肺疾病急性加重的研究进展  

Advances in acute exacerbation of connective tissue disease-associated interstitial lung disease

作　　者：毛伶俐 朱敏[1] 罗凤鸣[1] Mao Lingli;Zhu Min;Luo Fengming(Department of Respiratory and Critical Care Medicine,West China Hospital,Sichuan University,Chengdu 610041,China)

机构地区：[1]四川大学华西医院呼吸与危重症医学科,成都610041

出　　处：《国际呼吸杂志》2023年第1期36-42,共7页International Journal of Respiration

基　　金：国家自然科学基金(32070764);四川省科技计划(2021YFQ0030);西藏自治区科技计划项目(XZ202201ZY0002G);四川大学华西医院学科卓越发展1·3·5工程项目(ZYJC18021)。

摘　　要：结缔组织疾病相关间质性肺疾病急性加重与高病死率、健康和经济负担密切相关。由于缺乏公认的诊断标准,临床对该病的识别存在困难,缺乏循证的治疗手段。本文回顾现有文献,从流行病学、危险因素、临床特征、诊断、治疗等方面进行综述,以提高对该病的认识。Acute exacerbation of connective tissue disease-associated interstitial lung disease(AE-CTD-ILD)is closely associated with high mortality,health condition,and economic burden.Due to the lack of official diagnostic criteria,it is difficult to identify the disease in clinical practice.There also lacks therapy based on strong evidence.In order to improve the understanding of AE-CTD-ILD,this review summarizes the epidemiology,risk factors,clinical features,diagnosis,and treatment of the disease.

关 键 词：肺疾病 间质性 结缔组织疾病 流行病学 危险因素 诊断 治疗 急性加重 临床特征 

分 类 号：R593.2[医药卫生—内科学]