北京市医疗机构抗菌药物临床应用分级管理目录的循证制订  

Evidence-Based Formulation of Antibiotics Classification Management Lists in Beijing Medical Institutions

作　　者：徐晓涵[1,3,4] 周鹏翔 孔旭东[5] 曹照龙 程吟楚[1,3,4] 谷丽[7] 海沙尔江·吾守尔 贺蓓[2] 胡欣 刘朝晖[11] 刘清华 马小军[13] 马序竹 齐文杰 苏建荣[17] 王睿[18] 王晓玲[19] 徐英春[14] 闫盈盈[1,3,4] 杨旸[12] 应颖秋[1,4] 翟所迪[1,3,4] 赵志刚 甄健存 周颖[22] 朱光发 郑波[4,23] 杨毅恒 XU Xiao-han;ZHOU Peng-xiang;KONG Xu-dong;CAO Zhao-long;CHENG Yin-chu;GU Li;Haishaerjiang·Wushouer;HE Bei;HU Xin;LIU Chao-hui;LIU Qing-hua;MA Xiao-jun;MA Xu-zhu;QI Wen-jie;SU Jian-rong;WANG Rui;WANG Xiao-ling;XU Ying-chun;YAN Ying-ying;YANG Yang;YING Ying-qiu;ZHAI Suo-di;ZHAO Zhi-gang;ZHEN Jian-cun;ZHOU Ying;ZHU Guang-fa;ZHENG Bo;YANG Yi-heng(Department of Pharmacy,Peking University Third Hospital,Beijing 100191,China;Department of Pulmonary and Critical Care Medicine,Peking University Third Hospital,Beijing 100191,China;Beijing Pharmacy Center for Quality Control and Improvement,Beijing 100191,China;Institute for Drug Evaluation,Peking University Health Science Center,Beijing 100191,China;Department of Pharmacy,China-Japan Friendship Hospital,Beijing 100029,China;Department of Respiratory and Critical Care Medicine,Peking University People's Hospital,Beijing 100044,China;Department of Infection Diseases and Clinical Microbiology,Beijing Chaoyang Hospital,Capital Medical University,Beijing 100020,China;School of Pharmaceutical Sciences,Peking University,Beijing 100191,China;International Research Center for Medicinal Administration,Peking University,Beijing 100191,China;Department of Pharmacy,Beijing Hospital,Beijing 100730,China;Department of Gynecology,Beijing Obstetrics and Gynecology Hospital,Capital Medical University,Beijing Maternal and Child Health Care Hospital,Beijing 100026,China;Department of Pharmacy and Medical Equipment,Beijing Municipal Health Commission,Beijing 100053,China;Department of Infectious Medicine,Peking Union Medical College Hospital,Beijing 100730,China;Department of Clinical Laboratory,Peking Union Medical College Hospital,Beijing 100730,China;Department of Infectious Disease,Beijing Tsinghua Changgung Hospital,Tsinghua University,Beijing 102218,China;Department of Infectious Medicine,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China;Clinical Laboratory Center,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China;Room of Medicine Clinic

机构地区：[1]北京大学第三医院,药剂科,北京100191 [2]北京大学第三医院,呼吸与危重症医学科,北京100191 [3]北京市药学质量控制和改进中心,北京100191 [4]北京大学医学部药物评价中心,北京100191 [5]中日友好医院药学部,北京100029 [6]北京大学人民医院呼吸与危重症医学科,北京100044 [7]首都医科大学附属北京朝阳医院感染和临床微生物科,北京100020 [8]北京大学药学院,北京100191 [9]北京大学医药管理国际研究中心,北京100191 [10]北京医院药学部,北京100730 [11]首都医科大学附属北京妇产医院/北京妇幼保健院妇科,北京100026 [12]北京市卫生健康委员会药械处,北京100053 [13]中国医学科学院北京协和医学院北京协和医院,感染内科,北京100730 [14]中国医学科学院北京协和医学院北京协和医院,检验科,北京100730 [15]清华大学附属北京清华长庚医院感染性疾病科,北京102218 [16]首都医科大学附属北京友谊医院,感染内科,北京100050 [17]首都医科大学附属北京友谊医院,临床检验中心,北京100050 [18]中国人民解放军总医院药剂科药物临床研究室,北京100853 [19]首都医科大学附属北京儿童医院药学部,北京100045 [20]首都医科大学附属北京天坛医院药学部,北京100070 [21]北京积水潭医院药学部,北京100035 [22]北京大学第一医院,药学部,北京100034 [23]北京大学第一医院,临床药理研究所,北京100034 [24]首都医科大学附属北京安贞医院呼吸与危重症医学科,北京100029

出　　处：《中国药学杂志》2023年第2期188-194,共7页Chinese Pharmaceutical Journal

摘　　要：目的探索建立基于循证医学的药品目录遴选方法,并修订北京市医疗机构抗菌药物临床使用分级管理目录,为科学形成药品目录和合理应用抗菌药物提供支持。方法北京市卫生健康委员会建立多学科的目录工作组根据目录计划书,整合药品数据、药品证据和专家意见,按照纳入排除标准,通过德尔菲法对北京市医疗机构抗菌药物临床使用分级管理目录形成专家共识。结果遴选的目录共纳入99种药品,与上版目录相比,新增10种抗菌药物,调出38种抗菌药物;另有5种和13种抗菌药物分别上调和下调了管理级别。结论以循证医学思想和方法为指导,通过全面的证据和数据支持、结合多学科专家的经验、科学的共识方法,可以提高药品目录修订的科学性和合理性。OBJECTIVE To explore the establishment of drug list selection method based on evidence-based medicine,and torevise the Antibiotics Classification Management Lists in Beijing Medical Institutions,so as to provide supports for the scientific forma-tion of drug lists and the rational application of antibiotics.METHODS The Beijing Municipal Health Commission established a mul-tidisciplinary drug list working group to integrate drug data,drug evidence and expert opinions based on the plan of drug list,and toform expert consensus on the classification management list through the Delphi method according to the inclusion and exclusion criteria.RESULTS A total of 99 kinds of drugs were included in the selected classification management list.Compared with the previous clas-sification management list,10 kinds of antibacterial drugs were added,and 38 kinds of antibacterial drugs were called out.Except that5 kinds of antibacterial drugs were raised in management level,13 kinds of antibacterial drugs were downgraded in management level.CONCLUSION Guided by the thought and methods of evidence-based medicine,through comprehensive evidence and data support,combined with the experience of multidisciplinary experts,and scientific consensus methods,the scientificity and rationality of the revi-sion of the drug list can be improved.

关 键 词：抗菌药物分级管理 目录制订 循证医学 德尔菲法 

分 类 号：R95[医药卫生—药学]