电针干预苯丙胺类兴奋剂戒断者精神症状及生命质量的临床研究  

Clinical study of electroacupuncture intervention on mental symptoms and quality of life in amphetamine-type stimulant abstainers

作　　者：俞捷 梁艳[1] 顾尤 孔璟怡 施大庆 徐姹月 陈绘佳 YU Jie;LIANG Yan;GU You;KONG Jingyi;SHI Daqing;XU Chayue;CHEN Huijia(Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China;Institute of Rehabilitation for Drug Addiction,Shanghai Public Security Bureau,Shanghai 200439,China;Minhang Hospital Affiliated to Fudan University,Shanghai 201199,China)

机构地区：[1]上海中医药大学附属岳阳中西医结合医院,上海200437 [2]上海市公安局强制隔离戒毒所,上海200439 [3]复旦大学附属闵行医院,上海201199

出　　处：《上海中医药大学学报》2023年第1期38-44,共7页Academic Journal of Shanghai University of Traditional Chinese Medicine

基　　金：上海中医药大学预算内项目(2021LK090)。

摘　　要：目的:观察电针对苯丙胺类兴奋剂(ATS)戒断者的精神症状及生命质量的干预作用。方法:纳入88例ATS戒断者,随机分为常规治疗组、电针治疗组,每组各44例。常规治疗组患者经急性脱毒后,在给予健康宣教的基础上以自然戒断疗法为主;电针治疗组患者在常规干预的同时,给予电针治疗,每周治疗3次,共治疗10次。分别于治疗前和治疗1周、2周后及治疗结束时,评定并比较两组患者的苯丙胺戒断症状调查表(AWQ)、阳性与阴性精神症状量表(PANSS)和药物成瘾者的生命质量评定量表(QOL-DA)评分。结果:研究过程中,常规治疗组剔除病例1例,最终纳入统计分析者包括常规治疗组43例、电针治疗组44例。①治疗1周、2周后及治疗结束时,电针治疗组患者的AWQ评分较治疗前均降低(P<0.05);治疗2周后及治疗结束时,电针治疗组患者的AWQ评分低于常规治疗组(P<0.05)。②治疗1周、2周后及治疗结束时,两组患者的PANSS总分及阳性量表、一般精神病理量表评分较治疗前均降低(P<0.05),电针治疗组患者的PANSS阴性量表评分较治疗前亦降低(P<0.05),且电针治疗组患者的阳性量表评分低于常规治疗组(P<0.05);治疗2周后及治疗结束时,常规治疗组患者的PANSS阴性量表评分较治疗前亦降低(P<0.05),且电针治疗组患者的总分及阴性量表、一般精神病理量表评分均低于常规治疗组(P<0.05)。③治疗1周、2周后及治疗结束时,电针治疗组患者的QOL-DA评分较治疗前均升高(P<0.05),且电针治疗组患者的评分均高于常规治疗组(P<0.05)。结论:电针疗法可改善ATS戒断者的精神症状及生命质量,且起效时间短,其疗效随治疗时间的延长而逐渐增强。Objective: To observe the effect of electroacupuncture(EA) intervention on the mental symptoms and quality of life in amphetamine-type stimulant(ATS) abstainers. Methods: A total of 88 ATS abstainers were included and randomly divided into the conventional treatment group and EA treatment group, 44 cases in each group. After acute detoxification, the patients in the conventional treatment group were given natural withdrawal therapy on the basis of health education. The patients in the EA treatment group were given EA therapy based on the routine intervention, 3 times every week and a total of 10 times treatment were performed. Before treatment, after 1and 2 weeks of treatment, and at the end of treatment, the scores of amphetamine withdrawal questionnaire(AWQ), positive and negative syndrome scale(PANSS) and quality of life for drug addicts scale(QOL-DA) were assessed and compared between the two groups.Results: During the study, 1 case in the conventional treatment group was eliminated, finally 43 cases in the conventional treatment group and 44 cases in the EA treatment group were included in the statistical analysis.①After 1 and 2 weeks of treatment and at the end of treatment, the AWQ score of the EA treatment group was decreased compared with that before treatment(P<0.05). After 2 weeks of treatment and at the end of treatment, the AWQ score of the EA treatment group was lower than that of the conventional treatment group(P<0.05).②After 1 and 2 weeks of treatment and at the end of treatment, the total score of PANSS and the scores of positive scale and general psychopathological scale in the two groups were decreased compared with those before treatment(P<0.05), the score of negative scale in PANSS of the EA treatment group was also decreased compared with that before treatment(P<0.05), and the positive scale score of the EA treatment group was lower than that of the conventional treatment group(P<0.05). After 2 weeks of treatment and at the end of treatment, the score of negative scale in PANSS of the c

关 键 词：苯丙胺类兴奋剂 戒断者 电针 精神症状 生命质量 

分 类 号：R246.6[医药卫生—针灸推拿学]