大环化合物在高选择性分子印迹识别体系中的研究进展  

Research Progress of Macrocyclic Compounds in Highly Selective Molecular Imprinting Recognition System

作　　者：高静霞 王子安 张连明[1] 李建平[1] GAO Jing-Xia;WANG Zi-An;ZHANG Lian-Ming;LI Jian-Ping(College of Chemistry and Bioengineering,Guilin University of Technology,Guilin 541006,China)

机构地区：[1]桂林理工大学化学与生物工程学院,桂林541006

出　　处：《应用化学》2023年第1期24-39,共16页Chinese Journal of Applied Chemistry

基　　金：广西科技计划项目(No.桂科AD19110059);广西研究生教育创新计划项目(No.YCSW2022332)资助。

摘　　要：分子印迹技术(Molecular Imprinting Technology,MIT)因其预定性、专一性和适用性而被广泛应用于色谱分离、固相萃取、药物分析以及手性识别等领域。近些年来,研究者们将大环化合物引入MIT中,在增加识别位点的同时,有效改善了印迹聚合物材料的结构和性能,提高了对模板分子的选择性识别能力。本文重点综述了近10年来环糊精、杯芳烃、柱芳烃、冠醚和葫芦脲等大环化合物在分子印迹技术中的研究进展及应用,并对该领域的发展前景进行了展望。Molecular imprinting technology(MIT)has predetermination,recognition and usability,and has been widely used in chromatographic separation,solid phase extraction,drug analysis,chiral recognition and other fields.In recent years,researchers have introduced macrocyclic compounds into MIT,which not only increases the types of functional monomers,but also effectively improves the specificity of molecularly imprinted polymers and the selectivity of target molecules.In this paper,the research progress and application of macrocyclic compounds such as cyclodextrin,calixarene,pillararene,crown ether,cucurbituril and other supramolecular compounds in MIT in the past ten years are reviewed and its development prospects are prospected.

关 键 词：大环化合物 分子印迹 选择性 

分 类 号：O654[理学—分析化学]