磷脂管的体外组装及其在生物与化学领域的研究进展  

Research Progress of Assembly of Phospholipid Tube in Vitro and Its Potential Application in the Field of Biology and Chemistry

作　　者：毕洪梅 BI Hong-Mei(College of Biological and Food Engineering,Guangdong University of Petrochemical Technology,Maoming 525000,China)

机构地区：[1]广东石油化工学院生物与食品工程学院,茂名525000

出　　处：《应用化学》2023年第1期40-51,共12页Chinese Journal of Applied Chemistry

基　　金：广东省自然科学基金(Nos.2020A1515010522,2022A1515012070);广东省特色创新项目(No.2019KTSCX109);GDUPT人才科研项目(No.2019rc114)资助。

摘　　要：由磷脂组成的微管结构在有机体组织及器官中均有存在,在细胞间的物质传递及信息交流等方面起着重要作用。实现磷脂管在体外的简单快速组装是解析生命信息系统的良好途径。由于良好的生物相容性及支架结构特性,对磷脂管进行材料或结构修饰,是扩大其潜在应用的极佳手段。以磷脂管本身为载体以及以磷脂管为模板修饰构建的微纳米材料,在生物、材料及化学等方面的应用也取得了一系列成果。对磷脂管的体外组装及其在多个领域的应用研究进行了梳理归纳,重点对磷脂管的体外组装方式以及磷脂管在生物及化学等领域的应用等做了分类阐述与总结,并提出磷脂管在多功能纳米复合材料方面的未来发展及应用方向。Microtubules composed of phospholipids exist in both tissues and organs and play an important role in material transfer and information exchange between cells.Simple and rapid assembly of phospholipid tube in vitro is a good way to reveal and analyze the information system of life.Due to its good biocompatibility and scaffold structure,material or structural modification of phospholipid tube is the best way for expanding its potential application.A series of progress on biological,materials and chemical applications has also been made on the carrier using phospholipid tubes themselves as well as the micro/nanomaterials fabrication using the phospholipid tube as the template.In this review,the assembly of phospholipid tube in vitro and its application in many fields are summarized,mainly focusing on the classification of phospholipid tube assembly method in vitro and its application in biology and chemistry field,and the prospective development and application direction of phospholipids tube in multifunctional nanocomposite materials is put forward.

关 键 词：磷脂管 组装 携载 催化 识别 

分 类 号：O648[理学—物理化学]