日本乙型脑炎病毒感染宿主后引起相关信号通路变化的研究进展  

Research progress on changes of related signal pathways associated with Japanese encephalitis virus infection in host

作　　者：陈阊峥 汤德元[1] 杨志刚[1] 晏仁潭 韩超逸 罗柳 廖正波 袁盛林 陈旭[1] CHEN Changzheng;TANG Deyuan;YANG Zhigang;YAN Rentan;HAN Chaoyi;LUO Liu;LIAO Zhengbo;YUAN Shenglin;CHEN Xu(College of Animal Sciences,Guizhou University,Gui Yang 550025,China)

机构地区：[1]贵州大学、动物科学学院,贵州贵阳550025

出　　处：《中国兽医学报》2023年第1期199-203,共5页Chinese Journal of Veterinary Science

基　　金：黔科合支撑资助项目([2021]一般162);黔科合支撑资助项目([2018]2265)。

摘　　要：日本乙型脑炎(JE)是一种神经性人畜共患传染病,主要症状表现为中枢性神经炎症,尚未完全了解其致病机制,且目前尚无有效的治疗药物。近年来人们对于日本乙型脑炎病毒(JEV)感染后引起的相关信号通路变化进行深入研究,许多信号通路传导机制不断被发现,但仍缺乏系统性的探究,本文就JEV感染后引起的相关信号通路变化研究做综述总结,为JEV研究提供新的思路。Japanese encephalitis B is a neurozoonotic infectious disease.Its main symptom is central nervous inflammation.Its pathogenesis cannot be completely understood,and there is no effective therapeutic drug at present.In recent years,people have conducted in-depth research on the changes of relevant signal pathways caused by Japanese encephalitis virus infection.Many signal pathway transmission mechanisms have been found continuously,but there is no systematic exploration and summary.This paper summarizes the research on the changes of relevant signal pathways caused by Japanese encephalitis virus infection.It provides a new idea for the research of Japanese encephalitis virus.

关 键 词：日本乙型脑炎病毒 信号通路 细胞凋亡 免疫逃逸 

分 类 号：S852.65[农业科学—基础兽医学]